Search found 12 matches

by Jay Ess
Sat Mar 23, 2024 6:29 am
Forum: Prevention and Treatment
Topic: Bryan Johnson & His Longevity Protocol
Replies: 6
Views: 26761

Re: Bryan Johnson & His Longevity Protocol

He has some good advice. I started eating lentils because of him, so I owe him that. Frankly, his approach is expensive and very supplement heavy, and he doesn't always detail what specific supplements and foods helped to address what specific biomarkers, which makes the advice less useable than tha...
by Jay Ess
Fri Aug 04, 2023 8:15 am
Forum: Science and Research
Topic: MIND Diet fails to show any benefit in randomized clinical trial
Replies: 6
Views: 3034

Re: MIND Diet fails to show any benefit in randomized clinical trial

The other thing I would say about this study is that it didn't exactly show a failure of the diet: From baseline to year 3, improvements in global cognition scores were observed in both groups, with increases of 0.205 standardized units in the MIND-diet group and 0.170 standardized units in the cont...
by Jay Ess
Sat Jul 29, 2023 6:27 am
Forum: Science and Research
Topic: Advanced Glycation/sRAGE
Replies: 8
Views: 3906

Re: Advanced Glycation/sRAGE

circular wrote: Thu Jun 22, 2023 11:04 am They cook it in the can and who knows how high the heat is.
If this is the case, I'd also be concerned about how much aluminum is leached into the fish.
by Jay Ess
Sat May 27, 2023 5:18 am
Forum: Science and Research
Topic: Surgery, Anesthesia, & Aluminum
Replies: 22
Views: 4658

Re: Surgery, Anesthesia, & Aluminum

I am having total knee replacement surgery June 2023 and was stunned to find out that many of the best knee implants/prostheses contain titanium with aluminum and vanadium alloys. I have not been able to find out if this could be a problem in the future if aluminum ions leech into my body and brain...
by Jay Ess
Sun Jan 29, 2023 8:42 am
Forum: Prevention and Treatment
Topic: Blue Zones, specifically Seventh Day Adventists
Replies: 22
Views: 5738

Re: Blue Zones, specifically Seventh Day Adventists

Jan18 wrote: Sat Jan 28, 2023 11:29 am And the first thing I noticed is he eats 39 strawberries A DAY?!
Yeah, his diet is interesting... he's also eating about a pound of carrots a day. I like most of the foods he eats, but I haven't made time to eat those quantities.
by Jay Ess
Sat Jan 28, 2023 9:37 am
Forum: Science and Research
Topic: British Medical Journal - New Study Lifestyle and Memory Decline
Replies: 3
Views: 1584

Re: British Medical Journal - New Study Lifestyle and Memory Decline

One thing I note is that APOE4 carriers with a healthy lifestyle declined more slowly than APOE4 non-carriers with an unhealthy lifestyle. So that's encouraging.
by Jay Ess
Sat Jan 28, 2023 8:51 am
Forum: Prevention and Treatment
Topic: Blue Zones, specifically Seventh Day Adventists
Replies: 22
Views: 5738

Re: Blue Zones, specifically Seventh Day Adventists

If you really want to know what foods are taking you in the right or wrong direction, the suggestion I would give to anyone, APOE4 or otherwise, is to do what Michael Lustgarten does: https://www.youtube.com/watch?v=KI1nGnG1r8c In brief: Get a full blood test, enter the data in Aging.AI, make the di...
by Jay Ess
Sat Oct 29, 2022 6:26 am
Forum: Science and Research
Topic: The association of APOE genotype with COVID-19 disease severity
Replies: 6
Views: 1318

Re: The association of APOE genotype with COVID-19 disease severity

I'm pretty sure that is a statistically significant age difference (mean age of 39 in the mild group vs. mean age of 46 in the severe group.)
7 years is definitely clinically significant in any context... if it's not statistically significant then the sample size was too small.
by Jay Ess
Sat Oct 15, 2022 6:41 am
Forum: Prevention and Treatment
Topic: Still so worried about sleep
Replies: 16
Views: 1890

Re: Still so worried about sleep

I'm not in a position to say whether you'll be able to avoid Alzheimer's or not, but this really helped me: https://www.sleepio.com/

If it's not covered by your insurance, there may be some similar sleep training you can find.
by Jay Ess
Sun Jul 10, 2022 6:50 am
Forum: Science and Research
Topic: Plasmalogen levels modified by COVID
Replies: 0
Views: 273

Plasmalogen levels modified by COVID

Plasmalogen Loss in Sepsis and SARS-CoV-2 Infection

Given the relationship of plasmalogen levels to Alzheimer's, this may be of interest. One limitation here is that they were looking at septic patients, who are very ill.