Search found 767 matches

by MarcR
Sat Jun 08, 2024 11:21 am
Forum: ApoE4.Info, Inc.
Topic: Forum Site Performance Issues
Replies: 4
Views: 142

Re: Forum Site Performance Issues

Intermittently, I used to find notifications in my spam folder. Since I added admin@apoe4.info to my contacts, I think delivery to my primary folder has been consistent.
by MarcR
Wed Jun 05, 2024 12:36 pm
Forum: ApoE4.Info, Inc.
Topic: Forum Site Performance Issues
Replies: 4
Views: 142

Forum Site Performance Issues

We are experiencing intermittent slow responses and errors ... General Error SQL ERROR [ mysqli ] User apoeinfo_bb already has more than 'max_user_connections' active connections [1203] An sql error occurred while fetching this page. Please contact an administrator if this problem persists. ... and ...
by MarcR
Thu May 23, 2024 2:32 pm
Forum: Prevention and Treatment
Topic: Artificial Sweetener Drinks
Replies: 17
Views: 1020

Re: Artificial Sweetener Drinks

This is America, free speech is an inalienable right. When you registered for membership to this forum, you agreed to limit your speech to abide by the Community Guidelines by clicking the I agree to these terms button. These forums are not public, and the First Amendment is inapplicable to them. T...
by MarcR
Wed May 22, 2024 9:17 pm
Forum: Prevention and Treatment
Topic: Artificial Sweetener Drinks
Replies: 17
Views: 1020

Re: Artificial Sweetener Drinks

Hmm, the study linked in the first post of this topic is well short of "overwhelming" evidence. As a prospective study, it cannot show causation. In the authors' words: As our study was observational, we are unable to determine whether artificially-sweetened soft drink intake increased the...
by MarcR
Tue Jan 02, 2024 12:22 pm
Forum: Practitioner Reviews
Topic: Char Glenn, MD / Portland, OR
Replies: 11
Views: 31490

Re: Char Glenn, MD / Portland, OR

We have not interacted with Dr. Glenn for several years and do not know her current status.
by MarcR
Tue Apr 25, 2023 5:28 pm
Forum: Science and Research
Topic: Our first guest: Dr. Thomas Dayspring...
Replies: 181
Views: 144069

Re: Our first guest: Dr. Thomas Dayspring...

Does the hypothesis that LDL/ApoB causes dementia rely upon the hypothesis that LDL/ApoB causes arteriosclerosis? Essentially, if LDL harms blood vessels, poor circulation will impair the brain? I wonder if anyone is aware of a compelling study that demonstrates dementia causation directly.
anne from california wrote:
by MarcR
Tue Apr 25, 2023 9:43 am
Forum: Science and Research
Topic: Our first guest: Dr. Thomas Dayspring...
Replies: 181
Views: 144069

Re: Our first guest: Dr. Thomas Dayspring...

Anne, I wonder if you have seen the study discussed here. Also, there are a couple of relevant studies linked earlier in that topic, here.
anne from california wrote:
by MarcR
Mon Mar 20, 2023 12:27 am
Forum: Our Stories
Topic: High ldl-p and apob
Replies: 17
Views: 10239

Re: High ldl-p and apob

Thanks for directing me to this, Quantifier. I was not aware of it. I just spent an hour looking at the twitter thread and the Google Drive folder containing the analysis. Perhaps I'm missing it, but I don't see an upper limit to exclude people with familial hypercholesterolemia. In general, that's ...
by MarcR
Fri Mar 17, 2023 2:33 pm
Forum: Our Stories
Topic: High ldl-p and apob
Replies: 17
Views: 10239

Re: High ldl-p and apob

As a purely statistical analysis, Mendelian randomization is blind to functional factors. In a world beset by metabolic dysfunction and the resulting chronic disease, MR plausibly shows LDL as a causative factor within Group 1 ... But in this case, I think we are lumping a disease state together wit...
by MarcR
Fri Mar 17, 2023 12:05 pm
Forum: Our Stories
Topic: High ldl-p and apob
Replies: 17
Views: 10239

Re: High ldl-p and apob

Before tinkering with your body's cholesterol homeostasis, I think you should consider the possibility that nothing at all is amiss. Do you believe Peter Attia and Thomas Dayspring, or do you believe Vladimir Subbotin and your daily experience of health and wellbeing? More here . The hypothesis that...