Search found 41 matches

by KathleenC
Tue Jul 02, 2024 2:33 pm
Forum: Science and Research
Topic: Top AD Experts Debating New Targeted Biomarkers and Therapeutic Approaches in a New Era
Replies: 7
Views: 518

Re: Top AD Experts Debating New Targeted Biomarkers and Therapeutic Approaches in a New Era

Hi all - Found this fascinating 10-part new short video series on Neurology Live with top AD medical experts Richard Isaacson, MD (moderator) Sharon Cohen, MD Marwan Sabbagh, MD who discussed and debated the criticality of early intervention and evolving treatment strategies surrounding Alzheimer’s...
by KathleenC
Thu Jun 27, 2024 11:41 am
Forum: Science and Research
Topic: Klotho - rs9536314
Replies: 23
Views: 5156

Re: Klotho - rs9536314

Hi Sean, I'm guessing you've read or heard about this 2020 article: Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4 or this great explanation from Genetic Life Hacks: https://www.geneticlifehacks.com/klotho-apoe-e4/. Have to admit, when I saw it...
by KathleenC
Fri Mar 08, 2024 4:20 am
Forum: Prevention and Treatment
Topic: Methylene Blue AD Cure Celebration Thread!
Replies: 50
Views: 79017

Re: Methylene Blue AD Cure Celebration Thread!

T, thanks. That's what I thought. I confess my kitchen is filled with blue stains, but I think I now know how to put the powder in capsules carefully. It seems like the easiest approach, for me at least. My next question is about getting non-contaminated MB. This was helpful: https://docs.google.co...
by KathleenC
Fri Dec 22, 2023 6:30 am
Forum: Prevention and Treatment
Topic: Alzheimer's Disease Cured ! J11 Exclusive!
Replies: 15
Views: 18081

Re: Alzheimer's Disease Cured! J11 Exclusive!

Thanks so much for sharing this information!
by KathleenC
Sat Dec 16, 2023 5:31 am
Forum: Prevention and Treatment
Topic: Statins and Dementia studies
Replies: 19
Views: 45120

Re: Statins and Dementia studies

But this is all due to the fact that the high risk pool dropped out so you are left with low risk statin users who can handle the statin. You bring up a good point. Those who can't tolerate a statin for whatever reason (cognitive decline, myopathy, etc.) usually aren't included in these studies. BU...
by KathleenC
Fri Oct 20, 2023 9:49 am
Forum: Science and Research
Topic: Gut - Brain connection confirmed (according to this paper)
Replies: 2
Views: 4402

Re: Gut - Brain connection confirmed (according to this paper)

Very interesting. Thanks so much for sharing.

Kathleen
by KathleenC
Wed Sep 27, 2023 2:27 pm
Forum: Science and Research
Topic: Bumetanide for APOE4 Carriers
Replies: 7
Views: 7787

Re: Bumetanide for APOE4 Carriers

It gets even better, much better. New study today replicating earlier results, now with an adjusted odds ratio of 0.23, i.e., over 75% reduction in AD risk for people who took bumetanide for a mean duration of only 115 days at a typical oral dose of 1 mg. Loop diuretics association with Alzheimer’s...
by KathleenC
Thu Sep 14, 2023 3:34 pm
Forum: Meet-Ups
Topic: Virtual Meet-up (formerly called Book Club: The End of Alzheimer's Program)
Replies: 274
Views: 266554

Re: Virtual Meet-up (formerly called Book Club: The End of Alzheimer's Program)

Time flies...time for another Virtual Meet-up. We are going to try a Sunday afternoon (in the US) meeting this time. September 17 at 3:00-4:30 pm CDT. Bring your questions, discoveries, and curiosity. A calendar invitation with zoom link has been sent out to anyone who has expressed an interest in ...
by KathleenC
Thu Sep 14, 2023 6:42 am
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 79
Views: 222991

Re: Homotaurine (tramiprosate) appears to be a structure corrector

It seems that since homotaurine is tolerated with minimal side effects, outside of nausea for 20-25% of users, there is little downside risk to taking 300 mg of homotaurine per day while we await final study results coming next year. Is that your take as well? I have had no problems with the 200 mg...
by KathleenC
Thu Sep 14, 2023 5:48 am
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 79
Views: 222991

Re: Homotaurine (tramiprosate) appears to be a structure corrector

A press release today. Alzheon Reports Industry-Leading Biomarker, Brain Preservation and Clinical Benefits Following 24 Months of Treatment in Phase 2 Trial of Oral ALZ-801 (Valiltramiprosate) in Patients with Early Alzheimer’s Disease Unprecedented 28% Preservation of Hippocampal Volume Compared ...