Ah, thank you for the update. I received this note yesterday from my contact at Sano Genetics: I hope you are well. I wanted to reach out today for two reasons. First, it looks like an individual from your community successfully pre-screened for the study last week. We are working on getting that i...

Alexia, thank you for posting to the thread and gaining a preview of the excitement available for interns on the APOE4 site. This is the most exciting moment in the century long history of AD clinical research. It does not get better than this!... I have already ordered my 2 cans of cashews and cho...

Hi all. This phase of the APOLLOE4 study has concluded. The study organizers have asked me to let you know that this opportunity is no longer available. When/if they have further updates, we'll be happy to share them. Julie, I think the study that is no longer accepting participants is the the Gene...

...usually 2 g betain. 6 months ago I increased Bt to 7 g daily... 谢谢您的提醒。并且感谢您提供的降低同型半胱氨酸的配方，我想问下Bt是什么物质？我没查到。 The following is the English translation of the software, which may not be accurate. Please forgive me Thank you for your reminder. And thank you for the formula to reduce homocysteine，I ...

Does anyone have any concerns that none of the Alzheimer/vaccine studies were done with Shingrix but with Zostavax which a different type of vaccine? "FDA licensed Shingrix (GSK), a recombinant shingles vaccine on October 20, 2017; therefore, most Shingrix-vaccinated subjects are not included ...

Curious what everyone is thinking on this. Do you favor Shingrix or Zostavax or both? The CDC hasn't always been at the top of they game lately, but this resource on Shingrix lays out what seems to me to be a convincing case. . https://www.cdc.gov/vaccines/vpd/shingles/public/shingrix/index.html My...

Lecanemab given priority review with PDUFA of January 6, 2023. This is likely to be approval based on documented safety and efficacy of the outcome of reducing biomarkers of AD pathology: amyloid beta and tau There is also mention that full approval could be sought in March of 2023. I am not sure o...

I have the good fortune of being able to virtually attend this conference, so will post periodically what seem to be relevant results for ApoE4 carriers and those interested in current and upcoming clinical trials. Given the enormous scope of presentations and posters, no guarantees that I'll pick w...

From this short article reported by Reuters: Exclusive: Cassava Sciences faces U.S. criminal probe tied to Alzheimer's drug, sources say The U.S. Justice Department has opened a criminal investigation into Cassava Sciences Inc (SAVA.O) involving whether the biotech company manipulated research resu...

Hello! This article ( CETP Genotype Modifies the Effect of Apolipoprotein ε4 on Memory Decline in Older Adults ) shows that APOE4 carriers with CETPV405V experiences a lower cognitive decline rate. So for these of your with rs5882 mutated from A to G, you will probably have slower decline. Good new...