Search found 2118 matches

by NF52
Thu Dec 05, 2024 7:09 am
Forum: Practitioner Reviews
Topic: Doctors in Singapore, Kuala Lumpur, Bangkok and South East Asia
Replies: 2
Views: 28

Re: Doctors in Singapore, Kuala Lumpur, Bangkok and South East Asia

Hi, I recently discovered that I was a ApoE e4/e4 and I have been looking for a doctor to support me in fighting the gene. Doctors I have spoken to are all more or less telling me to wait until I get diagnosed with ADS, because they can't do much before. Obviously "preventive" methods exi...
by NF52
Wed Dec 04, 2024 9:44 am
Forum: Prevention and Treatment
Topic: Being keto adapted and social situations on Keto
Replies: 2
Views: 126

Re: Being keto adapted and social situations on Keto

Hello everyone, I have been on a ketogenic diet (with occasional cheating) for over 6 months now, and am pretty sure I am fat adapted. Looking at lists of "signs you are fat adapted", I pretty much check all the boxes. However, I am confused about wether or not I am also keto adapted, bec...
by NF52
Wed Dec 04, 2024 9:11 am
Forum: Prevention and Treatment
Topic: Questions about blood test results and risk assessment
Replies: 3
Views: 143

Re: Questions about blood test results and risk assessment

Good morning, I have been here before but not for more than a couple of years. I'm a 58 year old woman, apoe 3/4. My mom was also a 3/4 and my dad was never tested, so I'm assuming I got my 4 from my mom. I am trying to figure out if apoe4 works "silently" against us even with normal bloo...
by NF52
Thu Nov 21, 2024 7:32 am
Forum: Science and Research
Topic: Crushed Zizyphi spinosi (seed) prevents neurodegenerative diseases and reverses age-related cognitive decline in mice
Replies: 21
Views: 766

Re: Crushed Zizyphi spinosi (seed) prevents neurodegenerative diseases and reverses age-related cognitive decline in mic

The researchers found that simply dried and powdered ZSS was the most effective intervention compared to various other extracts they tested. A dose of 0.1mg/30g mouse (comes out to about 3.3mg/kg) was used for the dried ZSS powder. Not sure how much folks here like to play lab rat at home, but for ...
by NF52
Thu Nov 21, 2024 6:08 am
Forum: Science and Research
Topic: Crushed Zizyphi spinosi (seed) prevents neurodegenerative diseases and reverses age-related cognitive decline in mice
Replies: 21
Views: 766

Re: Crushed Zizyphi spinosi (seed) prevents neurodegenerative diseases and reverses age-related cognitive decline in mic

The researchers found that simply dried and powdered ZSS was the most effective intervention compared to various other extracts they tested. A dose of 0.1mg/30g mouse (comes out to about 3.3mg/kg) was used for the dried ZSS powder. Not sure how much folks here like to play lab rat at home, but for ...
by NF52
Wed Nov 20, 2024 6:39 pm
Forum: Getting Started
Topic: Genetic counseling
Replies: 13
Views: 1186

Re: Genetic counseling

The truth of the matter is, I'm afraid that if I share my genetic information with insurance companies, they will assume that I am destined to develop Alzheimer's, and therefore treat me like an Alzheimer's patient. I'm afraid that the state or some other agency will step in and make me their ward,...
by NF52
Mon Nov 18, 2024 8:03 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 169
Views: 340179

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

This seems like the right place to post an article from the Nov. 14 issue of Alzforum on a panel discussion of the AHEAD3-45 Clinical Trials. As the article notes: Lecanemab was approved for people with mild cognitive impairment or mild dementia due to Alzheimer’s, but trial data show it works bett...
by NF52
Mon Nov 18, 2024 7:35 pm
Forum: Prevention and Treatment
Topic: "Leqembi: Side Effects No Worse in Clinical Use Than They Were in Trial"
Replies: 0
Views: 86

"Leqembi: Side Effects No Worse in Clinical Use Than They Were in Trial"

Alzforum posted a summary of several presentations by clinicians in the U.S, UK, and Japan on numbers and safety data for Leqembi (lecanemab) at the recent CTAD (Clinical Trials on Alzheimer's Disease) conference. Details are available here: Leqembi: Side Effects No Worse in Clinical Use Than They W...
by NF52
Mon Nov 18, 2024 4:40 pm
Forum: Getting Started
Topic: Hello, i did a MyHeritage test!
Replies: 12
Views: 844

Re: Hello, i did a MyHeritage test!

... Regarding Promethease, I did subscribe and regarding ApoE section what they tell: - rs7412(C;C) part of APOE4 genoset evaluation -> this one I knew, quite standard and usual. - rs440446(C;G) increased risk in men for biliary conditions -> I'll disregard this one as a female & not related to...
by NF52
Sat Nov 16, 2024 12:41 pm
Forum: Prevention and Treatment
Topic: FDA approves "Kisunla" (donanemab) for MCI/Mild AD
Replies: 14
Views: 997

Re: FDA approves "Kisunla" (donanemab) for MCI/Mild AD

ARIA 3.PNG ARIA 2.PNG ARIA 1.PNG https://assets.ctfassets.net/mpejy6umgthp/4vbew8MSRVpgzDkYrcQzSU/45e7cd8dc17cb50b581582a5b2966f46/DV-021572_24wTB6-MDD.pdf Thank you for posting the slide presentation from the recent CTAD conference presentation on a trial using 4 different titration methods for do...