A little bit of history - the 1st gen commercial HRV monitors were bands placed around the chest and directly over the heart. As the technology improved, watches and wristbands were introduced. Now, the technology has improved and rings have been introduced. With that said, it is highly unlikely th...

Dad died last night. Mom has had AD for a long time. She knows me and my husband and remembers some things from long ago, but can't remember what she had for breakfast. She is not combative anymore. What is more merciful? To tell her that he died, and then she will have to be reminded over and over...

I am 48 almost 49. A quick recap of my story: a lifelong migraine sufferer had an MRI where multiple millimetric white matter hyperintensities were found . I have done so much testing and all they found is that I have one copy of the gene. So maybe these lesions came from the gene. I'm scared out o...

Hello everyone, Joined forum today. I am 65, 4/4, normal cognition (for now!), got my plasma pTau217 'positive' results yesterday with a value 0.82 (A test result >0.63 ng/L is positive and is consistent with a positive amyloid PET scan with 95% positive predictive value). My neurologist is setting...

https://www.sciencefocus.com/the-human-body/what-does-disease-smell-like Another article about different disease smells. Thanks for sharing these! I had forgotten reading about the wife who is a super-smeller and her help to researchers. The classic biomarker of Parkinson’s disease, which that woma...

New here bu have been reading some of your discussions for the past few years. My husband (just turned 40) is APOE4x1. His mother lives with us and has had Alzheimers since her early 60s (now 78) her mom had it as well and I think it goes back in the family quite a ways. While I try not to think ab...

As for Alz-801, I have been looking for updates often on the APOLLOE4 phase 3 trial as results were supposed to come out in 2024. I was beginning to fear that the results may have not been positive & thats why there have been no updates. The excerpt below if from press release I received via em...

Mark, thank you for your post and Nancy thank you for your very informative response. As for Alz-801, I have been looking for updates often on the APOLLOE4 phase 3 trial as results were supposed to come out in 2024. I was beginning to fear that the results may have not been positive & thats why...

Seeking Advice on Clinical Trials for Alzheimer's Treatment Options Hello, everyone. I’m a 59-year-old male with APOE 4/4, a positive PET scan, and a diagnosis of Mild Cognitive Impairment (MCI). I’m exploring participation in clinical trials as an alternative to currently approved drugs, given wha...

My recent labs: June 2023 Total Cholesterol 206 Triglycerides 55 HDL 73 LDL 126 October 2024 Total cholesterol 184 Triglycerides 79 HDL 63 LDL 106 ApoB 85 I am a 74-year-old woman. Last year, I was concerned about my high LDL, especially since I had a high Coronary Calcium score of 255 in 2019. In ...