Search found 1511 matches

by NF52
Wed Jun 29, 2022 6:30 pm
Forum: Science and Research
Topic: Researchers find two FDA-approved drugs that curb symptoms of Alzheimer’s disease
Replies: 2
Views: 51

Re: Researchers find two FDA-approved drugs that curb symptoms of Alzheimer’s disease

Looks promising?...... Looks intriguing, at the very least! Thanks for finding and sharing this, Greyhound. Below is an excerpt from the open access article https://alzres.biomedcentral.com/articles/10.1186/s13195-022-01020-9]Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and ...
by NF52
Wed Jun 29, 2022 5:59 pm
Forum: Our Stories
Topic: New here 4/4
Replies: 7
Views: 1912

Re: New here 4/4

I just read the post that CETP rs5882 G/G is related to long health life and 70% less risk of Alzhiemers! Doing my happy dance! I came to the forum to look up some SNPS and found this. I believe I will just stop for today and enjoy this great news. Thanks to all who help research and post Thanks so...
by NF52
Tue Jun 28, 2022 6:36 am
Forum: Our Stories
Topic: After 17 hours fast, only mild ketosis
Replies: 19
Views: 167

Re: After 17 hours fast, only mild ketosis

We started the Bredesen Protocol around July 2019. We have the support of a FM Doctor who happens also to be an MD. My role has been to take the book, and other inputs and interpret where we are in the process while being the best caretaker I can. It's my wife who has the cognitive decline. She is ...
by NF52
Tue Jun 28, 2022 5:28 am
Forum: Announcements and Events
Topic: Who's going to the free Drs Summit on Reversing Alzheimer's?
Replies: 6
Views: 504

Re: Who's going to the free Drs Summit on Reversing Alzheimer's?

I attended. That's how I found out about this community. :D Welcome 1ofMany! We're glad you found this community! Like you, I found this community after reading of Dr. Bredesen's work and going down lots of other "rabbit holes" of information as someone with two copies of ApoE4. This is a...
by NF52
Sat Jun 25, 2022 12:23 pm
Forum: Science and Research
Topic: Review: A multi-hit hypothesis for an APOE4-dependent pathophysiological state
Replies: 4
Views: 216

Re: Review: A multi-hit hypothesis for an APOE4-dependent pathophysiological state

APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians I wish they broke up the Native Americans by life style and/or location... Your wish is granted! For some background for others reading this, the current study used multiple cognitive and imaging ...
by NF52
Fri Jun 24, 2022 9:01 am
Forum: Our Stories
Topic: Unexpectedly found out I am a double APOE4
Replies: 9
Views: 439

Re: Unexpectedly found out I am a double APOE4

Hi Kate, another Kate here 😊, and also 4/4. I found out my status too when I was trying to find out if I had a brca mutation. I realised I’d been falsely reassured when I read the small print of the 23andme brca testing, so I paid for testing privately for full brca testing in a clinical genetics l...
by NF52
Fri Jun 10, 2022 11:23 am
Forum: Science and Research
Topic: Study shows people with a high omega-3 DHA level in their blood are at 49% lower risk of Alzheimer's
Replies: 3
Views: 215

Re: Study shows people with a high omega-3 DHA level in their blood are at 49% lower risk of Alzheimer's

And yes, it helps E4s. Further, the researchers noted that an increased intake of DHA might lower risk for developing AD, particularly in higher-risk individuals such as those carrying the APOE-ε4 allele, suggesting that they may benefit more from higher DHA levels than non-carriers. Summary is her...
by NF52
Tue Jun 07, 2022 8:46 am
Forum: Prevention and Treatment
Topic: Betablockers
Replies: 5
Views: 215

Re: Betablockers

Ok, thank you very much! I‘ll try to get my doctor to switch to a CCB or ARB instead of the betablockers. Actually now that I think of it my mum started on metoprolol a year ago. I wonder if that has contributed to her memory issues. Best Chris Chris, you said in your post that you are on metoprolo...
by NF52
Tue Jun 07, 2022 6:46 am
Forum: Prevention and Treatment
Topic: Betablockers
Replies: 5
Views: 215

Re: Betablockers

Hello kind and knowledgeable fellow ApoE4s, I read through your brilliant material but could not find an answer there. I assume some of you besides myself must be on betablockers for one reason or another (metoprolol for me). I need it for tachycardia, hypertension and migraine prevention. Now it h...
by NF52
Tue Jun 07, 2022 6:09 am
Forum: Science and Research
Topic: Plasmologens for Neuroregeneration
Replies: 17
Views: 1235

Re: Plasmologens for Neuroregeneration

Thanks NF52. Your addition makes it a lot easier to access these articles There are certainly some gold nuggets in the articles, only two are not immediately available. Have you got access to the article from Current Biology titled "Loss of functional heterogeneity along the CA3 transverse axi...