Search found 2801 matches

by Tincup
Thu Sep 28, 2023 4:21 pm
Forum: Science and Research
Topic: Tramiprosate: a silver bullet for 4/4 carriers?
Replies: 39
Views: 13854

Re: Tramiprosate: a silver bullet for 4/4 carriers?

Julie, do you mind sharing what brand of homataurine you purchased? This is the only supplement source I'm aware of, and all that have posted here about taking it are using this source, as far as I'm aware. See this thread. This is not an endorsement of this source's product, just the only one I'm ...
by Tincup
Mon Sep 25, 2023 7:18 pm
Forum: Prevention and Treatment
Topic: Is there research showing benefit of low fat diet for apoe4 phenotype?
Replies: 9
Views: 528

Re: Is there research showing benefit of low fat diet for apoe4 phenotype?

Very interesting. So when someone is in ketosis it looks like LDL spikes and, based on that, it makes sense that lowering fat intake would result in lower LDL numbers. In your experience, do LDL levels to fat metabolism describe a linear relationship or is there a threshold amount of fat intake (or...
by Tincup
Sat Sep 23, 2023 7:50 pm
Forum: Prevention and Treatment
Topic: Is there research showing benefit of low fat diet for apoe4 phenotype?
Replies: 9
Views: 528

Re: Is there research showing benefit of low fat diet for apoe4 phenotype?

3) @Plumster offered some evidence that low fat (and otherwise healthy) diet could help reduce LDL cholesterol, My personal experience is that my LDL is lower on low fat diets. I did that consistently for ~15 years, stopping around 15 years ago. My last test, in 2007 was Total 149 mg/dL, LDL 92 mg/...
by Tincup
Fri Sep 22, 2023 5:27 am
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 32
Views: 1955

Re: Homotaurine (tramiprosate) appears to be a structure corrector

Ah, darn, I'm sorry to hear that. When do you take your last dose of the day? It was earlier in the day. Thank you for this! I will pay very close attention to timing. I was doing 150mg (3 pills) morning and then later. Trying to do 100 mg three times wasn't happening as my daily life schedule is a...
by Tincup
Thu Sep 21, 2023 8:11 pm
Forum: Our Stories
Topic: Greetings from a 4/4 T1DM Apoe4 forum newbie!!
Replies: 7
Views: 219

Re: Greetings from a 4/4 T1DM Apoe4 forum newbie!!

My non T1 two cents. Have moderate sleep apnea (14.7 events per hour) and lobbying for a CPAP that Kaiser didn't approve. Have you tried taping your mouth during sleep? It can, in many mild to moderate sleep apnea cases, dramatically reduce the number of events. In this post there are three heart ra...
by Tincup
Thu Sep 21, 2023 5:54 am
Forum: Prevention and Treatment
Topic: Aluminum as a causal factor of Alzheimer's - Introduction of myself to the community
Replies: 230
Views: 85190

Re: Aluminum as a causal factor of Alzheimer's - Introduction of myself to the community

Had a consult on my 24 hour urine iodine test in this post and the mineral hair analysis (heavy metals shown in this post ). The consultant said my body was not holding onto any of the iodine I've been taking. He said this was indicative that my sodium iodide symporters weren't working. In the iodin...
by Tincup
Thu Sep 21, 2023 5:25 am
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 32
Views: 1955

Re: Homotaurine (tramiprosate) appears to be a structure corrector

It seems that since homotaurine is tolerated with minimal side effects, outside of nausea for 20-25% of users, there is little downside risk to taking 300 mg of homotaurine per day while we await final study results coming next year. Is that your take as well? I have had no problems with the 200 mg...
by Tincup
Thu Sep 14, 2023 5:54 am
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 32
Views: 1955

Re: Homotaurine (tramiprosate) appears to be a structure corrector

It seems that since homotaurine is tolerated with minimal side effects, outside of nausea for 20-25% of users, there is little downside risk to taking 300 mg of homotaurine per day while we await final study results coming next year. Is that your take as well? I have had no problems with the 200 mg...
by Tincup
Wed Sep 13, 2023 4:37 am
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 32
Views: 1955

Re: Homotaurine (tramiprosate) appears to be a structure corrector

A press release today. Alzheon Reports Industry-Leading Biomarker, Brain Preservation and Clinical Benefits Following 24 Months of Treatment in Phase 2 Trial of Oral ALZ-801 (Valiltramiprosate) in Patients with Early Alzheimer’s Disease Unprecedented 28% Preservation of Hippocampal Volume Compared t...
by Tincup
Tue Sep 12, 2023 10:37 am
Forum: Prevention and Treatment
Topic: Donanemab and Lecanemab
Replies: 9
Views: 528

Re: Donanemab and Lecanemab

So it is hard to know how he decided that the lecanemab didn't slow cognitive decline in women, especially because of. the charts from that Supplementary material shown below, all of which show that the 95% confidence interval of the mean of all results favors lecanemab in women--on cognitive and d...