Search found 116 matches

by thumperama
Sat Jul 30, 2022 1:51 pm
Forum: Science and Research
Topic: Potentially falsified Amyloid B research
Replies: 6
Views: 401

Re: Potentially falsified Amyloid B research

I exchanged messages with Charles Pillar ( https://twitter.com/cpiller ), the investigative reporter who authored the Science Magazine article, on Twitter. He said he will continue to track the case, and will publish more as developments arise. He said he believes resolution will take a lot of time....
by thumperama
Sat Jun 25, 2022 2:46 pm
Forum: Science and Research
Topic: Peter Attia hosts Benoit Arsenault for Lp(a) deep dive
Replies: 0
Views: 115

Peter Attia hosts Benoit Arsenault for Lp(a) deep dive

A typically high quality Dr Attia podcast. Sharing it here for a couple reasons: 1. Lots of folks in the community report high Lp(a) measurements along with their ApoE4 status. Benoit mentioned an ApoE/Lp(a) association, specifically, “ The apoE allele that increases the risk of heart attacks will a...
by thumperama
Tue Dec 14, 2021 12:09 am
Forum: Science and Research
Topic: Cataract Surgery Lowers Risk of AD
Replies: 6
Views: 539

Re: Cataract Surgery Lowers Risk of AD

Thanks, plumster. I noted : “ the only covariate that was more protective than cataract surgery was not having an APOE e4 allele”, referring to Figure 2.
by thumperama
Mon Dec 06, 2021 11:10 pm
Forum: ApoE4.Info, Inc.
Topic: 12/5/2021 forum software upgrade
Replies: 12
Views: 3237

Re: 12/5/2021 forum software upgrade

After a long hiatus, I’ve been visiting and reading again. Forum appears to operating well. Thanks for taking care of things!
by thumperama
Wed Jul 15, 2020 9:43 pm
Forum: Science and Research
Topic: Plasma ApoE Levels and Risk of Dementia—You Are the Company You Keep
Replies: 5
Views: 2194

Plasma ApoE Levels and Risk of Dementia—You Are the Company You Keep

“The findings by Koch et al1 therefore raise the possibility that composition of the HDL-associated proteome may be a key determinant of apoE-associated risk of AD and all-cause dementia. Identifying HDL-associated protein cargo and apoE-interacting proteins in HDL fractions may hence provide furthe...
by thumperama
Sat May 02, 2020 7:06 pm
Forum: Prevention and Treatment
Topic: Einkorn Sprouted Wheat
Replies: 19
Views: 6197

Re: Einkorn Sprouted Wheat

My wife and I purchased Einkorn flour about a decade ago. I don’t recall if it was sprouted, but I’m not sure that matters. We may a couple of batches of bread and it was a bit different than modern wheat but not remarkable, meaning the bread was quite good.
by thumperama
Sat May 02, 2020 5:56 pm
Forum: Prevention and Treatment
Topic: Moderate alcohol consumption protective against AD
Replies: 3
Views: 1869

Re: Moderate alcohol consumption protective against AD

Marc, without a well studied MOA, I have a hypothesis that alcohol consumption causes a dose-dependent impact on sleep; lots of N=1s report poor sleep, including objective metrics from devices like Oura. And we have good evidence for the role of sleep in AD. I would love to see alcohol studies inves...
by thumperama
Sat May 02, 2020 4:06 pm
Forum: ApoE4.Info, Inc.
Topic: Our 2019 Annual Report
Replies: 5
Views: 5289

Re: Our 2019 Annual Report

Julie, thanks for sharing the report. It’s great to see all the site-sponsored initiatives! Thanks to you and all of the other volunteers for this important work.
by thumperama
Sat May 02, 2020 3:51 pm
Forum: Prevention and Treatment
Topic: Art DeVany is back with a new book
Replies: 0
Views: 820

Art DeVany is back with a new book

For those who have been paying attention to paleo/ancestral health movement since its early days, you’ll likely recall Art as one of its original voices. I listened to an interview with him on STEM Talk, promoting his upcoming book, The Youthful Brain, partly a strategy to avoid AD. I enjoyed hearin...