Search found 46 matches

by Karina52
Tue Jul 11, 2023 7:07 am
Forum: Announcements and Events
Topic: Upcoming Gene Therapy Webinar
Replies: 4
Views: 2441

Upcoming Gene Therapy Webinar

Did you know? The LEAD study, sponsored by LEXEO Therapeutics, is currently the only clinical trial testing gene therapy in individuals with APOE4/E4 Alzheimer’s disease. LEXEO will be holding a webinar on Wednesday, August 2nd at 4 PM Eastern/1 PM Pacific for interested individuals to learn more ab...
by Karina52
Mon Jul 03, 2023 7:14 am
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 73
Views: 38164

Re: Using RAPA for AD prevention

Karina, As a Moderator of the forum, I've edited your post to remove your phone number. The best way to share that if you wish is through a Private Message (PM). You can send a Private Message to another user by using the envelope icon in the upper right hand corner of your screen, right next to yo...
by Karina52
Mon Jul 03, 2023 7:14 am
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 73
Views: 38164

Re: Using RAPA for AD prevention

yes, I was a patient of Dr. Smith for a while, but wasn't using his services so put my patient status on "pause". Thanks so much, Karina! That is so kind of you! I have been overwhelmed by all of the information and it will be so helpful to get insight from a person who has experience. I ...
by Karina52
Sat Jul 01, 2023 4:04 pm
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 73
Views: 38164

Re: Using RAPA for AD prevention

yes, I was a patient of Dr. Smith for a while, but wasn't using his services so put my patient status on "pause".
by Karina52
Sat Jul 01, 2023 11:06 am
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 73
Views: 38164

Re: Using RAPA for AD prevention

Randy Smith's concierge service (last year prices) was $199/month for access to him as needed (all virtual). Then he charges $395 a quarter for the lab work. He sends the phlebotomist to your house and draws blood (and gets urine sample) at your home. I live up in Roswell, and while I am not current...
by Karina52
Fri Jun 30, 2023 3:47 pm
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 49
Views: 37669

Re: Gene Therapy Trial for ApoE4 Homozygotes

Lexeo mentioned an interest in doing a webinar for the APOE4 community to learn more about the gene therapy.
Is this something of interest?
by Karina52
Fri Jun 30, 2023 3:42 pm
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 73
Views: 38164

Re: Using RAPA for AD prevention

Hi Kathleen, The doctor I get my rapamycin prescription from is Dr. Alan Green out of New York. Flew up there for the first visit. Since then it's all virtual visits. There is a concierge doctor, Randy Smith, right here in Atlanta who is a 4/4. He prescribes it as well but I'm not sure if he orders ...
by Karina52
Tue Jun 20, 2023 3:54 pm
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 49
Views: 37669

APOE4/4 gene trial

this is a message I received from Lexeo Therapeutics, who are running a HUMAN clinical trial replacing APOE4 with APOE2. "Are you (or someone you love) 50 years of age or older, experiencing memory loss due to Alzheimer’s disease, and have 2 copies of the APOE4 gene? You may qualify for a clini...
by Karina52
Sun Jan 22, 2023 6:39 am
Forum: Science and Research
Topic: Rapamycin prevents age-related brain vascular deterioration in rats
Replies: 27
Views: 9950

Re: Rapamycin prevents age-related brain vascular deterioration in rats

I continue to take rapamycin (Sirolimus). Dr. Green has increased my dose to 8mg a week, although I often still take just 6mg. It's been 14 months now. With anything putting me at risk of infection from its impact on the innate immune system (such as my recent cataract surgery), I temporarily stop i...
by Karina52
Sat Dec 03, 2022 9:46 am
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 49
Views: 37669

Re: Gene Therapy Trial for ApoE4 Homozygotes

Read a New York Times article yesterday about APOE2 gene therapy for 4/4 homozygotes. Since I am one of the admins of the APOE4/4 group on Facebook, I emailed one of the doctors (Dr. Samuel Gandy) last night and he responded this morning, introducing me to the research team at Weill Cornell. Dr. Mic...