Search found 7234 matches

by Julie G
Mon Dec 06, 2021 10:34 am
Forum: ApoE4.Info, Inc.
Topic: 12/5/2021 forum software upgrade
Replies: 3
Views: 59

Re: 12/5/2021 forum software upgrade

MarcR wrote: Sun Dec 05, 2021 10:24 pm This is complete. Please let me know if you see anything amiss.
Nothing amiss, my friend. It looks great. Please know how much your work is appreciated.
by Julie G
Fri Dec 03, 2021 12:32 pm
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 36
Views: 11808

Re: Gene Therapy Trial for ApoE4 Homozygotes

Hey Julie. I was wondering the same thing. The source was a post by ApropoE4 on April 29 in this thread. They didn’t link to the original source. Thank you both. Yes, I would still like to see the original source and can't find it. From a quick skim (as a layperson) this doesn't appear to be a prog...
by Julie G
Fri Dec 03, 2021 6:03 am
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 36
Views: 11808

Re: Gene Therapy Trial for ApoE4 Homozygotes

To add to NF52's great summary - the trial hasn't shown success in 40% of participants - rather it's shown APOE4 expression was down by 40% on average among participants, while APOE2 expression was maintained at least over the months that have passed. What is the source for this information? Might ...
by Julie G
Tue Nov 30, 2021 1:20 pm
Forum: Our Stories
Topic: Moving a loved one and re-homing a pet
Replies: 12
Views: 394

Re: Moving a loved one and re-homing a pet

My brother-in-law has recently passed, and my sister-in-law can not live on her own. I don't have anything of substance to add, but wanted you to know that I care. I also know that you're an amazing sister-in-law and am sending good energy to you and the whole family as you sort through this crisis...
by Julie G
Mon Nov 22, 2021 8:02 am
Forum: Our Stories
Topic: Introduction and Help With ApoE4 Diet
Replies: 14
Views: 1617

Re: Introduction and Help With ApoE4 Diet

I do not want to start disease in my coronary arteries, but I really do not like the ApoE4 foods. My triglyceride to HDL ratio as of my most recent lipid panel is 1.9, which means that I am insulin resistant and have pattern B LDL, so I should keep my cholesterol and LDL low. Hi Sabby! Overall, you...
by Julie G
Sun Nov 21, 2021 8:59 am
Forum: Science and Research
Topic: European Drug Regulation Advisors Recommend Against Approving Aduhelm in E.U.
Replies: 6
Views: 198

Re: European Drug Regulation Advisors Recommend Against Approving Aduhelm in E.U.

You can read a bit more about the Aduhelm associated death here: https://endpts.com/rbc-analyst-reports-aducanumab-case-file-points-to-the-controversial-alzheimers-drug-as-a-likely-cause-of-patient-death/ The FDA tells Endpoints News today that it’s aware of the death of a patient taking Biogen’s co...
by Julie G
Sat Nov 20, 2021 11:04 am
Forum: Science and Research
Topic: European Drug Regulation Advisors Recommend Against Approving Aduhelm in E.U.
Replies: 6
Views: 198

Re: European Drug Regulation Advisors Recommend Against Approving Aduhelm in E.U.

It's surprising that they only reference cost as their rationale for not recommending. Given the recent death associated with Aduhelm side effects, it seems like patient safety would have also played a part in their decision making. One patient death after treatment with Aduhelm was reported to the ...
by Julie G
Thu Nov 18, 2021 6:02 am
Forum: Prevention and Treatment
Topic: an E4/E4 brain CAN recover
Replies: 36
Views: 14788

Re: an E4/E4 brain CAN recover

Soooo, as someone who was just diagnosed with a mild concussion today and freaking out about it due to being a 3/4, reading this brought me tremendous relief. Sending virtual hugs, my friend. It's awful knowing you're an E4 and then sustaining a brain injury, but Stavia's post is VERY hopeful. My E...
by Julie G
Tue Nov 16, 2021 4:44 pm
Forum: Announcements and Events
Topic: Soft Launch of Our Metabolomic Project
Replies: 30
Views: 1779

Re: Soft Launch of Our Metabolomic Project

Julie, in the first post, you put in some links under point 3 that seem to provide 40% off to participants... https://prodrome.com/product/apoe4-rese ... lood-test/ https://prodrome.com/product/apoe4-rese ... up-bundle/ Is that not still available? And are you suggesting that we get the $1,300 bund...
by Julie G
Tue Nov 16, 2021 1:16 pm
Forum: Announcements and Events
Topic: Soft Launch of Our Metabolomic Project
Replies: 30
Views: 1779

Re: Soft Launch of Our Metabolomic Project

Friends, we have a few updates to add to our announcement regarding the launch of our metabolomic project, MOD4 (metabolomics, open-access, dataset for ApoE4.info). There were four grey areas that we have clarified with Prodrome and share with you here, to facilitate your participation in the projec...