Search found 7506 matches

by Julie G
Sun May 12, 2024 6:43 am
Forum: Science and Research
Topic: Apoe4 /4 a new genetic variant of Alzheimer’s ??
Replies: 60
Views: 8661

Re: Apoe4 /4 a new genetic variant of Alzheimer’s ??

A survey of apoe4.info user would be neither random nor imply that we are all following the same protocols, nor have the same demographics. It especially wouldn't show how many of us have elevated amyloid or tau. And having those would not predict at what age we might show cognitive symptoms. Great...
by Julie G
Tue Apr 30, 2024 4:24 am
Forum: Science and Research
Topic: Nigerian Alzheimer's Paradox?
Replies: 19
Views: 4576

Re: Nigerian Alzheimer's Paradox?

I have read about the parasite theories but what exactly, in specific language do parasites do that supposedly help? From what I understand, E4 carriers have overly activated innate immune systems. Parasites "dampen" that effect (reducing inflammation/improving cognition) by giving our im...
by Julie G
Fri Apr 19, 2024 1:11 pm
Forum: Prevention and Treatment
Topic: Let's solve ALZ. APOE4--Nature's/God's Original Design
Replies: 24
Views: 29102

Re: Let's solve ALZ. APOE4--Nature's/God's Original Design

I don't believe abeta causes AD only in E4s - Anyone can have assaults on the brain that could lead to damage and eventual AD. I'm thinking that E4s don't clean out the abeta and so have a double wammy. E4s need an especially good life style to avoid the abeta buildup in the first place. Beautifull...
by Julie G
Fri Apr 12, 2024 11:39 am
Forum: Prevention and Treatment
Topic: Let's solve ALZ. APOE4--Nature's/God's Original Design
Replies: 24
Views: 29102

Re: Let's solve ALZ. APOE4--Nature's/God's Original Design

Hi Julie. With the success of current trials, I'm thinking that ApoE4s may actually fit into the amyloid camp, whereas other variants who get AD would fall under Bredesen's multifactor causation model. Of course ApoE4's could be subject to both if their life styles have been poor... What leads you ...
by Julie G
Wed Apr 10, 2024 1:04 pm
Forum: Prevention and Treatment
Topic: Let's solve ALZ. APOE4--Nature's/God's Original Design
Replies: 24
Views: 29102

Re: Let's solve ALZ. APOE4--Nature's/God's Original Design

Our American society appears specifically vulnerable to the deception a pill will fix a problem, that a pill will override structurally flawed (addictive) consumption habits. Great post. We all wish it were that easy! ApoE4 must have some redeeming qualities or it wouldn't evolutionarily still be a...
by Julie G
Tue Apr 09, 2024 1:39 pm
Forum: Science and Research
Topic: talk about prevention strategies?
Replies: 12
Views: 55314

Re: talk about prevention strategies?

Below is a quote homocysteine from "Breaking Alzheimer’s: A 15 Year Crusade to Expose the Cause and Deliver the Cure" by Dayan Goodenowe, Chapter 19.
Amazing share, Tincup. I love the details of this stuff! Understanding the why helps us all refine our protocols.
by Julie G
Tue Apr 09, 2024 5:24 am
Forum: Science and Research
Topic: talk about prevention strategies?
Replies: 12
Views: 55314

Re: talk about prevention strategies?

Hit me with thoughts, advice, etc. Feel free to get technical if you want. I’m a biochemist working in a related field - though I feel like I know almost nothing useful and find it hard to keep up with the new developments. Hi there, fiver! Your regimen looks good. A few thoughts: -E4, in a dose de...
by Julie G
Fri Apr 05, 2024 1:49 pm
Forum: Science and Research
Topic: Top articles / recent research & helpful thoughts for ApoE4s
Replies: 18
Views: 73344

Re: Top articles / recent research & helpful thoughts for ApoE4s

What a wealth of information!!! Theresa, you are amazing.
by Julie G
Fri Mar 22, 2024 8:31 am
Forum: Getting Started
Topic: APOE4/4 makes it to age 86!
Replies: 13
Views: 21455

Re: APOE4/4 makes it to age 86!

As I read, understand about aphasia and dysarthria, these are "two distinct communication disorders that affect speech and language in different ways. Dysarthria is a motor speech disorder that affects the muscles used for speech, while aphasia is a language disorder that affects the ability t...
by Julie G
Thu Mar 21, 2024 6:59 am
Forum: Getting Started
Topic: APOE4/4 makes it to age 86!
Replies: 13
Views: 21455

Re: APOE4/4 makes it to age 86!

Her cognition is intact, yes. That's the most amazing part. She can still answer direct Yes/No questions with full comprehension even if her speech is severely impaired, limited. That's not supposed to happen for APOE4/4 people at age 86, they are supposed to be “gone” by now. Tell us more about th...