Search found 7310 matches

by Julie G
Sun Dec 04, 2022 2:59 pm
Forum: Prevention and Treatment
Topic: Lecanamab: Efficacy, Side Effects, and More
Replies: 18
Views: 726

Re: Lecanamab: Efficacy, Side Effects, and More

The CLARITY exclusions criteria indicates the capability of diagnosing microhemorrhages, and the MRIs are specifically timed frequently during titration to identify ARIA-H. Here's a partial list from CLARITY: Yes, thank you, NF52. I'm aware of the criteria but still have questions about HOW they ar...
by Julie G
Sun Dec 04, 2022 12:21 pm
Forum: Prevention and Treatment
Topic: Lecanamab: Efficacy, Side Effects, and More
Replies: 18
Views: 726

Re: Lecanamab: Efficacy, Side Effects, and More

Thanks all for your good wishes. We're taking it one day at a time. Late Friday night she was discharged to a rehab facility (love the timing!) but has only been approved for a short stay despite significant disabilities because of her insurance plan. We're scrambling to put a plan in place to ensur...
by Julie G
Fri Dec 02, 2022 10:53 am
Forum: Prevention and Treatment
Topic: Lecanamab: Efficacy, Side Effects, and More
Replies: 18
Views: 726

Re: Lecanamab: Efficacy, Side Effects, and More

It was more like 1-4 punch with stroke + TPA + CAA + lecanemab. Completely agree. Given the high prevalence of CAA for E4 carriers, are they giving baseline MRIs prior to lecanamb? If positive, is lecanamab contraindicated given the significant risk of bleeding? If this patient had a baseline MRI a...
by Julie G
Fri Dec 02, 2022 8:41 am
Forum: Prevention and Treatment
Topic: Olive oil not crucial to diet?
Replies: 3
Views: 173

Re: Olive oil not crucial to diet?

Maybe I skimmed too quickly, but this PR for a recent paper focused on specific flavonoids that protect against dementia. Isorhamnetin was one category that was recommended. Olive oil specifically falls into this category. Was there something else about olive oil that I missed? I think this is a gre...
by Julie G
Tue Nov 22, 2022 5:25 pm
Forum: Getting Started
Topic: Delirium
Replies: 28
Views: 4037

Re: Delirium

I think she just has chronic UTI . So sorry to hear this, Phil. She may very well have interstitial cystitis, in which her urinalysis will turn up normal but her bladder wall can be severely affected. A cystoscopy is the typical way to DX which may be too difficult for Robin to tolerate now. See th...
by Julie G
Thu Nov 17, 2022 3:25 pm
Forum: The Social Hour
Topic: Welcome Brother Chris!
Replies: 2
Views: 155

Welcome Brother Chris!

Chris Hemsworth just learned that he's an ApoE4/4. Guided by Peter Attia, he's proactively taking control of his health. What an amazing role model for his generation! Read more here.
by Julie G
Thu Nov 17, 2022 9:48 am
Forum: Prevention and Treatment
Topic: Hormone Replacement Therapy E4 Women
Replies: 746
Views: 282062

Re: Hormone Replacement Therapy E4 Women

The following is the English translation of the software, which may not be accurate. Please forgive me Smart Tian, how frustrating not to have any guidance. The one thing I will mention is that B vitamins are typically taken in the AM and magnesium threonate and progesterone in the PM. Combing them...
by Julie G
Mon Nov 14, 2022 10:52 am
Forum: Prevention and Treatment
Topic: Hormone Replacement Therapy E4 Women
Replies: 746
Views: 282062

Re: Hormone Replacement Therapy E4 Women

OK, thanks for your reply. My mother took it. My mother is 57 years old and has entered into a manic period. She put estradiol and progesterone in her drink and gave it to my mother. There are other supplements (mainly DHA and lipoic acid. Julie G for reference). They are very effective. My mother ...
by Julie G
Mon Nov 14, 2022 4:43 am
Forum: Science and Research
Topic: Beer hops compounds could help protect against Alzheimer’s disease
Replies: 9
Views: 424

Re: Beer hops compounds could help protect against Alzheimer’s disease

“Alzheimer’s Disease Prevention through Natural Compounds: Cell-Free, In Vitro, and In Vivo Dissection of Hop (Humulus lupulus L.) Multitarget Activity” https://www.eurekalert.org/news-releases/970332 Fascinating, thanks for sharing, Greyhound. Your input is valued and welcome here. I found a recen...