Search found 1256 matches
- Sun Feb 16, 2025 6:37 am
- Forum: Science and Research
- Topic: Brain bleeds double dementia risk, APOE4s at greater risk
- Replies: 0
- Views: 45
Brain bleeds double dementia risk, APOE4s at greater risk
Weill Cornell Medicine researchers have found that intracranial hemorrhages, or “brain bleeds” double a person’s risk of developing dementia later in life. This according to this Neuroscience News article just published on Feb 15, 2025. Brain Bleeds Double Dementia Risk . We’ve all probably heard ab...
- Sat Feb 15, 2025 1:06 pm
- Forum: Science and Research
- Topic: New policy capping NIH "indirects" at 15%
- Replies: 12
- Views: 290
Re: New policy capping NIH "indirects" at 15%
I don't have answers, but I do have concerns. On a personal level, as an ApoEε4/4, I am concerned at the impact to research. I have a strong family history of -4 related health issues and have witnessed/experienced first-hand the great financial burden, stress, emotional strain, and inadequate avail...
- Sat Feb 15, 2025 5:20 am
- Forum: The Social Hour
- Topic: Book: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
- Replies: 1
- Views: 4220
Re: Book: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
This piece, published by STATNEWS How the ‘amyloid mafia’ took over Alzheimer’s research gives a taste of the book, Doctored . It was adapted from one of the chapters and written by the book's author. I found it interesting, thought I'd share in case anyone else is interested in this subject that ha...
- Fri Feb 14, 2025 6:34 pm
- Forum: The Social Hour
- Topic: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
- Replies: 4
- Views: 93
Re: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
I have a friend who was diagnosed with MCI with a It's folks like your friend that this paper was written for. As stated in the NewsMedical article, According to physicians who care for people with Alzheimer's, many patients found it difficult to understand what the clinical trials results - presen...
- Fri Feb 14, 2025 6:04 pm
- Forum: The Social Hour
- Topic: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
- Replies: 4
- Views: 93
Re: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
I just read this and I was interested in the quote about how it is an expensive drug but might be worth it, since it would reduce the need for expensive assisted living. But I thought, that's not really the case. Doesn't it just delay assisted living needs for most people. Not to say it isn't usefu...
- Fri Feb 14, 2025 6:59 am
- Forum: The Social Hour
- Topic: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
- Replies: 4
- Views: 93
How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
This paper Assessing the clinical meaningfulness of slowing CDR-SB progression with disease-modifying therapies for Alzheimer's disease published by the Alzheimer’s Association on Feb 13, 2025 provides information that can help patients and caregivers weigh the benefits of these drugs against the co...
- Fri Feb 14, 2025 5:58 am
- Forum: Science and Research
- Topic: APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians
- Replies: 3
- Views: 131
Re: APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians
APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians https://pmc.ncbi.nlm.nih.gov/articles/PMC4066890/#:~:text=Some%20have%20suggested%20that%20APOE,environments%20%5B1%2C8%5D. You can read about that and a little more on the impact of APOE4 on nati...
- Wed Feb 12, 2025 6:05 am
- Forum: Science and Research
- Topic: APOE4 finding with a way to return cells to a healthy state
- Replies: 0
- Views: 85
APOE4 finding with a way to return cells to a healthy state
For those unfamiliar, Dr Hussein Yassine runs the Yassine Lab at USC. His lab specializes in lipid metabolism and nutrition’s affect on the brain and Alzheimer’s disease with a specific interest in the APOE4 allele. Researchers from his lab just published this paper: Cellular senescence induced by c...
- Mon Feb 03, 2025 9:59 am
- Forum: Prevention and Treatment
- Topic: Sleep maintenance issues. Am I doomed?
- Replies: 9
- Views: 3759
Re: Sleep maintenance issues. Am I doomed?
Please guide me on what to do I'm so scared these 2 weeks will age me. Three days every week I sleep 8hrs or more with ONLY seroquel cause I don't have to wake up for work and it's no problem at all staying asleep. Sleep IS important. One thing our welcome intern didn't point out is that our organi...
- Sun Feb 02, 2025 4:46 pm
- Forum: Science and Research
- Topic: Top articles / recent research & helpful thoughts for ApoE4s
- Replies: 24
- Views: 95563
Re: Top articles / recent research & helpful thoughts for ApoE4s
Below are the research papers that specifically addressed APOE4 and were published in January 2025 The abstracts of each paper and links to full paper access and can be found in the ApoE4.info wiki: A deeper dive into ApoE4 These do not necessarily represent every single paper that has been publishe...