Search found 1256 matches

by TheresaB
Sun Feb 16, 2025 6:37 am
Forum: Science and Research
Topic: Brain bleeds double dementia risk, APOE4s at greater risk
Replies: 0
Views: 45

Brain bleeds double dementia risk, APOE4s at greater risk

Weill Cornell Medicine researchers have found that intracranial hemorrhages, or “brain bleeds” double a person’s risk of developing dementia later in life. This according to this Neuroscience News article just published on Feb 15, 2025. Brain Bleeds Double Dementia Risk . We’ve all probably heard ab...
by TheresaB
Sat Feb 15, 2025 1:06 pm
Forum: Science and Research
Topic: New policy capping NIH "indirects" at 15%
Replies: 12
Views: 290

Re: New policy capping NIH "indirects" at 15%

I don't have answers, but I do have concerns. On a personal level, as an ApoEε4/4, I am concerned at the impact to research. I have a strong family history of -4 related health issues and have witnessed/experienced first-hand the great financial burden, stress, emotional strain, and inadequate avail...
by TheresaB
Sat Feb 15, 2025 5:20 am
Forum: The Social Hour
Topic: Book: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
Replies: 1
Views: 4220

Re: Book: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's

This piece, published by STATNEWS How the ‘amyloid mafia’ took over Alzheimer’s research gives a taste of the book, Doctored . It was adapted from one of the chapters and written by the book's author. I found it interesting, thought I'd share in case anyone else is interested in this subject that ha...
by TheresaB
Fri Feb 14, 2025 6:34 pm
Forum: The Social Hour
Topic: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
Replies: 4
Views: 93

Re: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?

I have a friend who was diagnosed with MCI with a It's folks like your friend that this paper was written for. As stated in the NewsMedical article, According to physicians who care for people with Alzheimer's, many patients found it difficult to understand what the clinical trials results - presen...
by TheresaB
Fri Feb 14, 2025 6:04 pm
Forum: The Social Hour
Topic: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
Replies: 4
Views: 93

Re: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?

I just read this and I was interested in the quote about how it is an expensive drug but might be worth it, since it would reduce the need for expensive assisted living. But I thought, that's not really the case. Doesn't it just delay assisted living needs for most people. Not to say it isn't usefu...
by TheresaB
Fri Feb 14, 2025 6:59 am
Forum: The Social Hour
Topic: How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?
Replies: 4
Views: 93

How much time will treatment with leqembi (lecanemab) and kisunla (donanemab) buy?

This paper Assessing the clinical meaningfulness of slowing CDR-SB progression with disease-modifying therapies for Alzheimer's disease published by the Alzheimer’s Association on Feb 13, 2025 provides information that can help patients and caregivers weigh the benefits of these drugs against the co...
by TheresaB
Fri Feb 14, 2025 5:58 am
Forum: Science and Research
Topic: APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians
Replies: 3
Views: 131

Re: APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians

APOE ε4 is not associated with increased risk for Alzheimer’s disease and dementia in American Indians https://pmc.ncbi.nlm.nih.gov/articles/PMC4066890/#:~:text=Some%20have%20suggested%20that%20APOE,environments%20%5B1%2C8%5D. You can read about that and a little more on the impact of APOE4 on nati...
by TheresaB
Wed Feb 12, 2025 6:05 am
Forum: Science and Research
Topic: APOE4 finding with a way to return cells to a healthy state
Replies: 0
Views: 85

APOE4 finding with a way to return cells to a healthy state

For those unfamiliar, Dr Hussein Yassine runs the Yassine Lab at USC. His lab specializes in lipid metabolism and nutrition’s affect on the brain and Alzheimer’s disease with a specific interest in the APOE4 allele. Researchers from his lab just published this paper: Cellular senescence induced by c...
by TheresaB
Mon Feb 03, 2025 9:59 am
Forum: Prevention and Treatment
Topic: Sleep maintenance issues. Am I doomed?
Replies: 9
Views: 3759

Re: Sleep maintenance issues. Am I doomed?

Please guide me on what to do I'm so scared these 2 weeks will age me. Three days every week I sleep 8hrs or more with ONLY seroquel cause I don't have to wake up for work and it's no problem at all staying asleep. Sleep IS important. One thing our welcome intern didn't point out is that our organi...
by TheresaB
Sun Feb 02, 2025 4:46 pm
Forum: Science and Research
Topic: Top articles / recent research & helpful thoughts for ApoE4s
Replies: 24
Views: 95563

Re: Top articles / recent research & helpful thoughts for ApoE4s

Below are the research papers that specifically addressed APOE4 and were published in January 2025 The abstracts of each paper and links to full paper access and can be found in the ApoE4.info wiki: A deeper dive into ApoE4 These do not necessarily represent every single paper that has been publishe...