For ApoE4 carriers, can the answer be as simple as keeping LDL low beginning in early adulthood? I find it difficult to accept that there’s such limited research on young adults in their 20s and 30s with ApoE4. Given all the variables that seem to contribute to Alzheimer's, and the other conditions...

Swil211 wrote: ↑Mon Mar 20, 2023 11:55 am Have you had a full panel to determine if you any protective SnPs or whatever a previous poster suggested?

I was tested in 2014 and have the raw data from 23andme to check on SnPs that are protective or not so protective when I learn about them.

I am a 29 year old female with an unremarkable medical history. My husband and I decided it would be fun to do 23andme a few weeks ago. When the results came back last week, I was shocked to find out I’m a 4/4. There is no known family history of dementia or Alzheimer’s on either side of my family....

Oops, forgot to quote you to assure you saw my response. So to amend: Aricept and other cholinesterase inhibitors are currently prescribed against Alzheimers. From the Info I gathered it is clear, that there are no positive long term effects, e.g. a 2017 Canadian review study, https://www.healthline...

Do you have Dr Bredesen’s first book, The End of Alzheimer’s ? He discusses Aricept (donepezil) in numerous places, mostly its temporary efficacy and drawbacks, including this: First, blocking the breakdown of acetylcholine does not affect the cause or progression of Alzheimer’s disease. The disease...

Tincup wrote: ↑Tue Mar 14, 2023 5:51 pm the salt pathway converting glucose to fructose

Also known as the polyol pathway that converts glucose and salt to fructose in the body.

I don't use facebook. What a shame. Look at the papers/articles you’ve missed that were posted on https://www.facebook.com/apoe4.info in just the past week. • Neurodegeneration, Mitochondria, and Antibiotics • What Are The Health Benefits Of Cold Water Swimming? • Rationale for a Multi-Factorial Ap...

richhahn wrote: ↑Mon Mar 13, 2023 8:00 pm

Did you find this study from our March 2nd ApoE4.info Facebook post? https://www.facebook.com/apoe4.info

This recently published paper has been causing quite a stir. Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism? Published earlier this month (March 2023), the lead author is Dr Richard J Johnson. He is a resea...

We had this thread where people have shared their experiences:
viewtopic.php?p=81056&hilit=photobiomodulation#p81056

More ATP is helpful, but the bigger picture is taking care of your mitochondria. https://wiki.apoe4.info/wiki/Mitochondria