NF52: Thanks for this update! I know at least one Alzheimer's Disease Research Center (ADRC) who is gearing up for the expected requests for fully approved anti-amyloid treatments and all the logistics and resources that will be required to treat folks safely. I have heard that many such centers are...

Chicago Girl: Glad you are "sticking" with it! My AHEAD study coordinator reported that many centers are having difficulty retaining subjects. I suspect that this is due to many factors. Among them is the time committment and the fact that the changes or stability in cognitive status and d...

Chicago Girl: Another helpful installment in your AHEAD journey. I also wish you had been negative or at least moderate in your Beta-Amyloid scan. Hopefully the MRI will confirm your continued elligibility for the trial. I have had 8 MRI's in the first 29 months AHEAD study and 1 for the previous an...

Nancy; Thank you for your eloquent and thoughtful description and discussion of the issues of participating in a clinical trial and especially being "pre-clinical Alzheimers." In this regard, I have been more open with friends and family regarding my risk factors. I have also done public p...

Chicagogirl: Great description of your screening for the AHEAD study. I am 2 years into the Ahead-3 arm of the study (visit 24). I have had one verified microhemorrage, but no other side-effects of which I am aware. Because of the microhemorrage early in the study, my neurologist thinks that I am pr...

Samantha, NF52, and Sonoma Mike: Thank you for your warm welcome to the group and for some useful ideas and resources.

I learned about my APOE4/E4 status about a year ago and it was confirmed by a second DNA analysis. Not happy about that, but I decided to get involved with the Alzheimer's Association doing volunteer public policy advocacy work and participating in the Generation I study and am now taking 50mg of CN...