Search found 10 matches

by Nevada
Sun Feb 11, 2024 11:16 am
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

Nancy, Thanks for posting all those changes and improvements to the AHEAD protocols. I hope that it will encourage more participation and better retention of participants. As you alluded, one important advantage of participating in an Alzheimer's study or clinical trial is establishing an ongoing re...
by Nevada
Wed Feb 07, 2024 2:49 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

I am in week 124 of the Ahead 3 study and just received and signed a revised Informed consent form yesterday for the study which includes two new provisions. The first is the option of a 2 year open label extension (treatment with Lecanemab) if you complete the study. The second is a 2 year open lab...
by Nevada
Sat Jan 13, 2024 12:28 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

I am now in week 121 of the Ahead study and receiving monthly infusions. Since I have passed the halfway point, I received the second Amyloid-beta and Tau PET scans and received my 9th MRI for this study. I asked the MRI technician if the MRI protocol had changed because it felt like it took much lo...
by Nevada
Thu Jun 01, 2023 3:23 pm
Forum: Prevention and Treatment
Topic: Medicare PartB to cover anti-amyloid treatments
Replies: 2
Views: 944

Re: Medicare PartB to cover anti-amyloid treatments

NF52: Thanks for this update! I know at least one Alzheimer's Disease Research Center (ADRC) who is gearing up for the expected requests for fully approved anti-amyloid treatments and all the logistics and resources that will be required to treat folks safely. I have heard that many such centers are...
by Nevada
Thu Jun 01, 2023 3:00 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

Chicago Girl: Glad you are "sticking" with it! My AHEAD study coordinator reported that many centers are having difficulty retaining subjects. I suspect that this is due to many factors. Among them is the time committment and the fact that the changes or stability in cognitive status and d...
by Nevada
Fri Mar 31, 2023 3:40 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

Chicago Girl: Another helpful installment in your AHEAD journey. I also wish you had been negative or at least moderate in your Beta-Amyloid scan. Hopefully the MRI will confirm your continued elligibility for the trial. I have had 8 MRI's in the first 29 months AHEAD study and 1 for the previous an...
by Nevada
Fri Feb 24, 2023 7:29 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

Nancy; Thank you for your eloquent and thoughtful description and discussion of the issues of participating in a clinical trial and especially being "pre-clinical Alzheimers." In this regard, I have been more open with friends and family regarding my risk factors. I have also done public p...
by Nevada
Wed Feb 22, 2023 5:12 pm
Forum: Prevention and Treatment
Topic: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)
Replies: 130
Views: 310289

Re: AHEAD 3-45 STUDY CLINICAL TRIAL (LECANEMAB - BAN 2401)

Chicagogirl: Great description of your screening for the AHEAD study. I am 2 years into the Ahead-3 arm of the study (visit 24). I have had one verified microhemorrage, but no other side-effects of which I am aware. Because of the microhemorrage early in the study, my neurologist thinks that I am pr...
by Nevada
Mon Mar 04, 2019 3:32 pm
Forum: Our Stories
Topic: New Member Introduction
Replies: 4
Views: 2246

Re: New Member Introduction

Samantha, NF52, and Sonoma Mike: Thank you for your warm welcome to the group and for some useful ideas and resources.
by Nevada
Sun Mar 03, 2019 3:51 pm
Forum: Our Stories
Topic: New Member Introduction
Replies: 4
Views: 2246

New Member Introduction

I learned about my APOE4/E4 status about a year ago and it was confirmed by a second DNA analysis. Not happy about that, but I decided to get involved with the Alzheimer's Association doing volunteer public policy advocacy work and participating in the Generation I study and am now taking 50mg of CN...