Search found 5486 matches

by circular
Sun Aug 14, 2022 10:38 am
Forum: Prevention and Treatment
Topic: Still trying to make sense if it is worth APOE4 to get a vaccine for Shingles and VZV?
Replies: 10
Views: 374

Re: Still trying to make sense if it is worth APOE4 to get a vaccine for Shingles and VZV?

I didn't see a study on this using Shingrix as a variable associated with functioning level since it was approved in 2017 and suspect that no one has studied this because a 2-dose drug would be expected to perform well and any study wouldn't be likely to have a surprising result or add to clinical ...
by circular
Mon Aug 01, 2022 11:27 am
Forum: Prevention and Treatment
Topic: Still trying to make sense if it is worth APOE4 to get a vaccine for Shingles and VZV?
Replies: 10
Views: 374

Re: Still trying to make sense if it is worth APOE4 to get a vaccine for Shingles and VZV?

I think I was vaccinated for chickenpox when I was a child (but can’t recall), and trying to determine if it is worth getting another vaccine based on the data coming out about the connection between Alzheimer’s and HSV1. By the way I tested and currently have the HSV1 antibodies. Personally, it wa...
by circular
Fri Jul 29, 2022 1:52 pm
Forum: Prevention and Treatment
Topic: The $100 Genome has Arrived? AD Breakthrough!
Replies: 16
Views: 788

Re: The $100 Genome has Arrived? AD Breakthrough!

They have a humanity family tree under construction which could be extremely powerful in searching for disease variants. You could simply locate yourself in this tree and report your phenotype to some database. The large variant risks might immediately pop out when even a few people in the tree rep...
by circular
Sun Jul 24, 2022 5:16 pm
Forum: Prevention and Treatment
Topic: The $100 Genome has Arrived? AD Breakthrough!
Replies: 16
Views: 788

Re: The $100 Genome has Arrived? AD Breakthrough!

Yes, it's true that they gave up on the ICAD name quite a while ago, though the replacement AAIC, I mean it's not even pronouncable. ACK? ICK? J11 dares to be different. I can't pronounce an acronym with three consecutive vowels and a soft consonant; ain't gonna happen, not even gonna try. ICAD? No...
by circular
Wed Jul 20, 2022 12:11 pm
Forum: Meet-Ups
Topic: Virtual Meet-up (formerly called Book Club: The End of Alzheimer's Program)
Replies: 170
Views: 31106

Re: Virtual Book Club: MiHigh Infrared Blanket

I also don't have time to delve into the tradeoffs between infrared and near infrared saunas, so any feedback about that would be helpful too. I did a quick search and found this overview comparing near, mid, and far infrared saunas as a starting point for research. It seems that each wavelength ra...
by circular
Wed Jul 20, 2022 11:07 am
Forum: Our Stories
Topic: Endurance athlete... how do I fuel?
Replies: 9
Views: 1507

Re: Endurance athlete... how do I fuel?

You can edit down their post if you like, as long as you don't disturb the beginning and ending brackets with the word "quote" in them! By the way, in case it's not come up before, the easiest way I've found to edit a post I'm quoting, as in the one just above, is before clicking on the q...
by circular
Tue Jul 19, 2022 7:33 pm
Forum: Prevention and Treatment
Topic: The $100 Genome has Arrived? AD Breakthrough!
Replies: 16
Views: 788

Re: The $100 Genome has Arrived? AD Breakthrough!

Thank you for your response Circ! This is now getting so exciting! We are now days away from ICAD! This will be epic. There are multiple topline reportables that are now imminent ... ... and then there's Clarity and then there's Gantenu so much to celebrate! I need to stock up for the celebration ....
by circular
Tue Jul 19, 2022 2:26 pm
Forum: Prevention and Treatment
Topic: Estrogen and choline
Replies: 4
Views: 358

Re: Estrogen and choline

According to Perspective: Estrogen and the Risk of Cognitive Decline: A Missing Choline(rgic) Link? there is evidence that the main way estrogen treatment prevents or slows down cognitive decline is by increasing expression of the PEMT gene (encoding phosphatidylethanolamine N-methyltransferase), a...
by circular
Sun Jul 17, 2022 2:14 pm
Forum: Meet-Ups
Topic: Virtual Meet-up (formerly called Book Club: The End of Alzheimer's Program)
Replies: 170
Views: 31106

Re: Virtual Book Club: MiHigh Infrared Blanket

Infrared Sauna Blanket: Here is the US website for MiHIGH https://www.mihigh.com I was hoping this might be on sale as part of Amazon Prime, but no dice. Is it possible that some of the cheaper sauna blankets are just as good? Does this only cost more because maybe it was the first one out? I reali...
by circular
Sat Jul 16, 2022 4:13 pm
Forum: Science and Research
Topic: New research on NR and Alzheimer's
Replies: 0
Views: 108

New research on NR and Alzheimer's

Nicotinamide riboside and caffeine partially restore diminished NAD availability but not altered energy metabolism in Alzheimer's disease Thus, although NR and caffeine can partially restore diminished NAD availability, increasing NAD alone may not be sufficient to boost or restore energy metabolis...