Another question, regarding the Resting heart rate. Mi mi band 4 tells me that my Resting heart rate is usually around 60 to 63 bpm. I have read that the typical RHR is between 60 to 100, with athletes being able to go down to 40. And also, usually (except for some diseases), "the lower the bet...

Interesting thread. I own a Xiaomi mi band 4, and I am doubtful about the quality of information of the sleep tracker. In general, it recognizes relatively well the start and end times of my sleep (not perfect, though) but it systematically gives me a low deep sleep time, around 1h10min. I usually g...

Thank you for the answer.

Could one say that 18 hours is at least as good as 14 or 16 hours? Or 14-16 hours is really the sweet spot for fasting?

I have seen that in the Bredesen protocol, intermittent fasting is an important part of it. At least 12 hours of fasting per day are recommended, but for APOE4 people, I believe it is stated that it is best between 14 and 16 hours. A question I have is: is coffee considered to break the fast? (I ass...

Following the Bredesen protocol, I bought some melatonin pills, just to experiment. In general, I go to sleep very early, around 9pm, and usually I wake up at around 4:30am (naturally, without any alarm clock). I usually do not feel tired when I wake up (on the contrary, I am quite energetic, and hu...

I have not been able to find in Bredesen's book a recipe of when to take each supplement (maybe there is, but I have not found it). Of course, melatonin is before sleeping. But what about the other pills? B12 / folate / D3 & K2 / ...? Does it matter when to take them? All at the same time? Separ...

Thank you for the answers. I hope I can learn more!

I do not know if having these high levels suggest I do not need the methylated versions, or not. In other words: methylated B vitamins help to increase, among others, B12 and folate (for people whose B12 and folate are low, and not increasing even taking non-methylated vitamins), or even if one has...

Hello, I am new here, with an APOE4 and MTHFR and MRR risk alelles. As a consequence, homocystein is a key issue for me. I am starting to supplement with methylated B vitamins. But a few months ago (before I knew I was APOE4, and I started to take any supplement), I did a blood test, and I had high ...

Hello, I am a 44-year old European man, with APOE3/4 (rs429358(C;T) and rs7412(C;C)), and I have the risk alleles in MTHFR (rs1801131(A;C) and rs1801133(C;T)) and MTRR (rs1801394(A;G)). In addition to this (unrelated to APOE4, but important for health, due to a high magnitude of 4, according to Prom...