Search found 1171 matches

by TheresaB
Sun May 12, 2024 11:56 am
Forum: Science and Research
Topic: Does the protectiveness of APOE 2 cancel the 4, in a 2/4?
Replies: 10
Views: 36264

Re: Does the protectiveness of APOE 2 cancel the 4, in a 2/4?

A friend tells me they are APOE 2/4. Does that exist? If so, does their 2 cancel out their 4? I know 2 is protective, at least when paired with other numbers. Yes, there is such a thing as a 2/4, but the 2 does not cancel out the 4. According to this paper, Association of APOE e2 genotype with Alzh...
by TheresaB
Sat May 11, 2024 6:37 am
Forum: Science and Research
Topic: Apoe4 /4 a new genetic variant of Alzheimer’s ??
Replies: 70
Views: 12061

Re: Apoe4 /4 a new genetic variant of Alzheimer’s ??

FYI, this paper was shared on May 8th on our sister Facebook website, https://www.facebook.com/apoe4.info, which should be accessible to all whether or not they have a facebook account. Needless to say, this post attracted a number of comments, here is what Dr Dale Bredesen wrote about this paper in...
by TheresaB
Fri Apr 12, 2024 2:34 am
Forum: Science and Research
Topic: Why do different types of saturated fat affect the ApoE4 brain differently?
Replies: 4
Views: 17583

Re: Why do different types of saturated fat affect the ApoE4 brain differently?

However, based on my experience, I am increasingly suspicious that it is not saturated fat per se that is the cause. It might be the form of that saturated fat. Try reading the ApoE4.info wiki: Coconut Oil, MCT oil, and other Ketone/Cognition Boosters (salts, esters) . I think that would help expla...
by TheresaB
Wed Apr 10, 2024 6:03 am
Forum: Science and Research
Topic: talk about prevention strategies?
Replies: 12
Views: 55784

Re: talk about prevention strategies?

Anyone want to talk about prevention strategies? The biggies for prevention that are typically cited are diet, exercise, sleep, reducing chronic stress and avoiding toxins. Although the devil is in the details. For example, there are folks who are convinced a carnivore diet is the only way to go, a...
by TheresaB
Thu Apr 04, 2024 3:01 pm
Forum: Science and Research
Topic: Top articles / recent research & helpful thoughts for ApoE4s
Replies: 19
Views: 75086

Re: Top articles / recent research & helpful thoughts for ApoE4s

1st quarter 2024 In addition to this website, we (ApoE4.info) have a Facebook page https://www.facebook.com/apoe4.info followed by thousands where current research/articles or just thoughts of interest to ApoE4s are posted. The posts are available to all whether or not a person has a Facebook accou...
by TheresaB
Thu Apr 04, 2024 1:28 pm
Forum: Prevention and Treatment
Topic: Omega 3
Replies: 6
Views: 40180

Re: Omega 3

Hi can someone please share the best brand and how much omega 3 should be taken daily for 4/4. . I can’t believe no one has responded! Placing importance on Omega-3 consumption is one of the incontrovertible tenants for ApoE4s! It’s a little disconcerting if no one else has knowledge on this. This ...
by TheresaB
Thu Mar 21, 2024 6:15 am
Forum: Science and Research
Topic: Root cause of Alzheimer's may be fat buildup in brain cells, especially in ApoE4s?
Replies: 6
Views: 14774

Root cause of Alzheimer's may be fat buildup in brain cells, especially in ApoE4s?

From this article, Root cause of Alzheimer's may be fat buildup in brain cells, research suggests published by Medical Xpress on 19 Mar 2024: Prior research has suggested that Alzheimer's disease is caused by a buildup of beta-amyloid in plaques that grow between nerve cells. Other work has also imp...
by TheresaB
Fri Mar 08, 2024 8:00 am
Forum: Prevention and Treatment
Topic: Donanemab and Lecanemab
Replies: 53
Views: 270027

Re: Donanemab and Lecanemab

Just announced, the FDA is delaying its approval of Donanemab. Excerpt from the New York Times, The Food and Drug Administration has decided to delay action on a closely watched Alzheimer’s drug, donanemab, which the agency was widely expected to approve this month. The F.D.A. will instead require d...
by TheresaB
Thu Mar 07, 2024 4:35 pm
Forum: Getting Started
Topic: ApoE4 and life expectancy/longevity
Replies: 12
Views: 27847

Re: ApoE4 and life expectancy/longevity

This paper was posted on the ApoE4.info Facebook page : and just published 7 days ago (Mar 1, 2024): How are APOE4, changes in body weight, and longevity related? Insights from a causal mediation analysis This finding is in line with the idea that the detrimental effect of APOE4 on longevity is, in ...
by TheresaB
Mon Feb 26, 2024 6:35 am
Forum: Prevention and Treatment
Topic: Why Enhancing Metabolic Health Could be the Key to Preventing Alzheimer's Disease
Replies: 0
Views: 13765

Why Enhancing Metabolic Health Could be the Key to Preventing Alzheimer's Disease

This video Why Enhancing Metabolic Health Could be the Key to Preventing Alzheimer's Disease by neurologist Dr David Perlmutter was posted on the ApoE4.info Facebook page yesterday (Feb 25, 2024) and has attracted a good amount of interest, so I thought I’d share it here. He starts by reviewing rece...