Search found 1153 matches

by TheresaB
Thu Mar 07, 2024 4:35 pm
Forum: Getting Started
Topic: ApoE4 and life expectancy/longevity
Replies: 12
Views: 27649

Re: ApoE4 and life expectancy/longevity

This paper was posted on the ApoE4.info Facebook page : and just published 7 days ago (Mar 1, 2024): How are APOE4, changes in body weight, and longevity related? Insights from a causal mediation analysis This finding is in line with the idea that the detrimental effect of APOE4 on longevity is, in ...
by TheresaB
Mon Feb 26, 2024 6:35 am
Forum: Prevention and Treatment
Topic: Why Enhancing Metabolic Health Could be the Key to Preventing Alzheimer's Disease
Replies: 0
Views: 13757

Why Enhancing Metabolic Health Could be the Key to Preventing Alzheimer's Disease

This video Why Enhancing Metabolic Health Could be the Key to Preventing Alzheimer's Disease by neurologist Dr David Perlmutter was posted on the ApoE4.info Facebook page yesterday (Feb 25, 2024) and has attracted a good amount of interest, so I thought I’d share it here. He starts by reviewing rece...
by TheresaB
Mon Feb 19, 2024 6:09 am
Forum: Prevention and Treatment
Topic: Modifiable risks and APOE 4/4
Replies: 7
Views: 17231

Re: Modifiable risks and APOE 4/4

Does following the practices Dr. Attia promotes decrease the risk to normal level? Assuming the majority of those with the 3/4 and 4/4 that get AD did not take any preventable measures such as exercise or proper diet. I'm not familiar with Dr Attia's ApoE4 protocol, I do know I appreciate most of w...
by TheresaB
Tue Feb 13, 2024 4:30 am
Forum: Prevention and Treatment
Topic: KetoFlex question
Replies: 2
Views: 1817

Re: KetoFlex question

I apologize if this is a very basic question. I'm trying to learn more about the KetoFlex 12/3 diet and I found a book on Amazon titled "Keto Flex" by Ben Azadi. My question is, is this the same diet at the Bredesen KetoFlex 12/3? I was hoping to learn more about how to implement the diet...
by TheresaB
Thu Feb 08, 2024 5:48 am
Forum: Science and Research
Topic: Question about new research on lysosomal autophagy
Replies: 2
Views: 13716

Re: Question about new research on lysosomal autophagy

I read a story today about a study that came out in January about druggable sites in ApoE4 and it found something they referred to as CBA2 as a candidate for a drug to improve lysosomal autophagy. Story: https://medicalxpress.com/news/2024-02-team-potential-alzheimer-drug.html Research: https://www...
by TheresaB
Wed Feb 07, 2024 7:16 am
Forum: Prevention and Treatment
Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
Replies: 1808
Views: 404461

Re: Celebration Thread! Biogen is going to the FDA with Aducan.

Last month CBS's 60 minutes broadcast an episode on “celebratory” news of a neurosurgeon addressing Alzheimer’s through focused ultrasound to open the blood-brain barrier in order to apply the anti-amyloid antibody aducanumab. The treatment did indeed reduce amyloid — BUT DID NOT REPORT ANY COGNITIV...
by TheresaB
Wed Feb 07, 2024 6:56 am
Forum: Prevention and Treatment
Topic: APOE 4/4 - Wisdom on telling siblings/children
Replies: 7
Views: 16327

Re: APOE 4/4 - Wisdom on telling siblings/children

I'm in an APOE 4/4 in a large family with no family history of dementia*. I have five siblings in their 50s/60s and 2 kids in their 20's. None of them have had DNA tests as far as I can tell, but my kids must have at least one E4 and odds are most of my siblings are one E4 or worse. Here's my story...
by TheresaB
Tue Feb 06, 2024 10:36 am
Forum: Getting Started
Topic: 55 years old Asian lady with subject cognitive decline
Replies: 8
Views: 15787

Re: 55 years old Asian lady with subject cognitive decline

Welcome Tony, your English is impressive! For carbohydrate, which types of carbohydrate will you recommend? I saw sugar and cereal were all banned from list. You're right, not all carbs are created equal. Maybe a visual will help, the KetoFlex pyramid ketoflex brain pyramid.jpg You see that non-star...
by TheresaB
Tue Feb 06, 2024 8:17 am
Forum: Our Stories
Topic: New, almost 50, with 1 copy Apoe4 and a family history.
Replies: 8
Views: 16052

Re: New, almost 50, with 1 copy Apoe4 and a family history.

You are already doing many important things that will help delay/avoid dementia. Good for you! I am here because I still have a slim hope that prevention or delay might be possible, so I would like to learn what I can. I also am interested in others stories. I am here to tell you there is hope! I wi...
by TheresaB
Tue Feb 06, 2024 6:43 am
Forum: Prevention and Treatment
Topic: Phyllodulcin shows potential for treating Alzheimer
Replies: 6
Views: 1395

Re: Phyllodulcin shows potential for treating Alzheimer

Thanks Theresa for sharing. Unfortunately I can’t open the page. Can you please check the link? I linked to the wiki's main page, if you scroll down, the article is there, but I'll make it easier, here's the link to the exact ApoE4.info wiki page: Beneficial (and some negative) Plant/Natural Chemic...