Search found 1093 matches

by floramaria
Sat Dec 18, 2021 7:37 pm
Forum: Prevention and Treatment
Topic: sleep
Replies: 17
Views: 6816

Re: sleep

I need to buy something to stop the 1:30 am "omg I am so hot" wake-ups. I have some questions - For those who have used a cooling system for a while, which one do you use? Do you still like it? How noisy is it? I wake up if an ant breathes near me. How do you keep it clean, since you can'...
by floramaria
Sat Dec 18, 2021 7:09 pm
Forum: Science and Research
Topic: BCG Vaccine to lower risk?
Replies: 2
Views: 342

Re: BCG Vaccine to lower risk?

I’m wondering if anyone knows/has thoughts on BCG vaccine to lower the risk of AD? https://www.researchgate.net/publication/330329850_Can_immunization_with_Bacillus_Calmette-Guerin_BCG_protect_against_Alzheimer's_disease I came across a study just finalizing (https://clinicaltrials.gov/ct2/show/NCT...
by floramaria
Sat Dec 18, 2021 6:58 pm
Forum: Science and Research
Topic: KLOTHO: Good news for 20% of us!
Replies: 18
Views: 4794

Re: KLOTHO: Good news for 20% of us!

I have found Promethease to be really unreliable; ie, a number of times the result Promethease shows is not the same as what is in my 23andMe raw data. I trust 23andMe more, so I never go with Promethease results anymore. I check my 23andMe raw data, and if they don't cover something, I take Promet...
by floramaria
Thu Dec 16, 2021 8:44 pm
Forum: Our Stories
Topic: ApoE 4/4: Grateful, but need some hope
Replies: 3
Views: 251

Re: ApoE 4/4: Grateful, but need some hope

I have integrated so many of the lifestyle changes since finding this group. My labs are pretty good at this point! I mostly follow a keto-flex 12/3 diet (I actually fast more like 14 hours) and I exercise. I was tested for sleep apnea and my oxygenation is great when sleeping on my side (which is ...
by floramaria
Thu Dec 16, 2021 2:04 pm
Forum: Prevention and Treatment
Topic: Optimal Coq10 levels?
Replies: 6
Views: 283

Re: Optimal Coq10 levels?

Hi all, I'm wondering what is optimal serum levels ug/mL for Coq10? Is it better to take Coq10 or Ubiquinol? Is Pqq and Quercetin very different? Mine was 0.57 ug/mL last spring, which my doctor found too low. What should I aim for? Thanks for your thoughts! Hi Plumster, Serum levels of CoQ10 are n...
by floramaria
Wed Dec 15, 2021 9:05 pm
Forum: Our Stories
Topic: lightweight newbie
Replies: 6
Views: 198

Re: lightweight newbie

Yes, I'm trying the ketoflex 12/3. I do make the almond bread and use nut butter, guacamole, or olive oil 'butter' on it but have not yet tried an almond-crust pizza. Is there a recipe available for the almond crust? I also make the almond/chia chips that are good with guacamole/salsa. Where could ...
by floramaria
Wed Dec 15, 2021 8:42 pm
Forum: Science and Research
Topic: KLOTHO: Good news for 20% of us!
Replies: 18
Views: 4794

Re: KLOTHO: Good news for 20% of us!

I was genotyped just last month at 23andme on their new v5 chip and I was told this was not included. It's frustrating they would report APOE but not include the genes that might modify its effect. Hi 75Perent, I haven't tried this recently, but in the past, including earlier this year, it was poss...
by floramaria
Mon Dec 13, 2021 2:05 pm
Forum: Our Stories
Topic: lightweight newbie
Replies: 6
Views: 198

Re: lightweight newbie

Hello, I’m Deb. Apo E3/E4. My goal is to gain back some of those lost 15 pounds because I felt better when I had them. I’m pretty sure that gaining weight is a problem for more than just me. I would very much like to hear some solutions (other than drinking a cup of EVOO every day). Hi Deb, Welcome...
by floramaria
Sat Dec 11, 2021 12:53 pm
Forum: Our Stories
Topic: 26 and 4/4
Replies: 14
Views: 3970

Re: 26 and 4/4

However I am 37 and right now they aren’t close to any cures or even any guaranteed prevention. I don’t know if they will come up with anything by the time I’m the age to start having symptoms. And personally I feel like that’s too late. Us 4/4 are building up plaques all our lives so unless they f...
by floramaria
Fri Dec 10, 2021 8:22 am
Forum: Science and Research
Topic: Microglial correlates of late life physical activity
Replies: 2
Views: 258

Re: Microglial correlates of late life physical activity

Significance statement Physical activity relates to better cognitive aging and reduced risk of neurodegenerative disease, yet the cellular and molecular pathways linking behavior-to-brain in humans are unknown. Animal studies indicate that increasing physical activity leads to decreased microglial ...