Search found 215 matches

by Brian4
Sun Jul 16, 2023 12:40 pm
Forum: Prevention and Treatment
Topic: Why Krill Oil Beats Fish Oil
Replies: 23
Views: 13935

Re: Why Krill Oil Beats Fish Oil

I recently started looking into krill oil and discovered that most formulations contain sorbitol. Sorbitol might not be as safe as once thought.

Anyone have a recommendation of krill oil without sorbitol?

Thanks,
Brian
by Brian4
Tue Jul 11, 2023 12:25 am
Forum: Science and Research
Topic: Using neuroprotective adjuvants in general anesthesia
Replies: 10
Views: 18940

Re: Using neuroprotective adjuvants in general anesthesia

Good luck with the surgery, and thanks for the wonderfully useful and hopeful information! One thing I'll add: there are some suggestive studies that fasting before GA can protect the brain. Fortunately, being fasted is typically part of the recommended prep for most major surgery, but it might be b...
by Brian4
Sat Jul 01, 2023 5:47 am
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 49
Views: 71563

Re: Gene Therapy Trial for ApoE4 Homozygotes

Hi Karina. I think this is a great idea!
by Brian4
Wed Jan 18, 2023 7:32 am
Forum: Science and Research
Topic: Rare variations of the APOE ε4 gene allele (R251G) can DRASTICALLY reduce the risk of AD
Replies: 5
Views: 1511

Re: Rare variations of the APOE ε4 gene allele (R251G) can DRASTICALLY reduce the risk of AD

Hi everyone. Whole genome sequencing has come down so much in price that it might be worth having it done. Then you can look up all these variants as research reveals them. I look up the variants by sucking the gargantuan genome file into a text reader that can handle huge files (the program is call...
by Brian4
Fri Dec 02, 2022 10:21 pm
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 49
Views: 71563

Re: Gene Therapy Trial for ApoE4 Homozygotes

Here's a bit more up-to-date info (more patients) from CTAD:

https://www.nytimes.com/2022/12/02/heal ... erapy.html

Brian
by Brian4
Wed Sep 28, 2022 4:44 pm
Forum: Prevention and Treatment
Topic: Genetic variant in 30% of Europeans that protects against Alzheimer's
Replies: 7
Views: 905

Re: Genetic variant in 30% of Europeans that protects against Alzheimer's

Thanks Petri.

For those who don't know, to reverse and translate, click on the gear icons to the right in the genome browser.

Brian
by Brian4
Fri Sep 16, 2022 4:55 am
Forum: Science and Research
Topic: Thoughts on Paxlovid?
Replies: 2
Views: 626

Re: Thoughts on Paxlovid?

Hi Kristin-Marie- From everything I've read, paxlovid is safe. Also from everything I've read, SARS-CoV-2 is not safe, esp. not for the brain. Even mild cases of COVID-19 are associated with damage, possibly permanent, to many organs, including the brain. No study has been done, that I'm aware of, l...
by Brian4
Tue Aug 09, 2022 12:52 am
Forum: Prevention and Treatment
Topic: The $100 Genome has Arrived? AD Breakthrough!
Replies: 16
Views: 2367

Re: The $100 Genome has Arrived? AD Breakthrough!

Brian4, wow a year? That is closer than I would have thought. That's my educated guess. Could be wrong, but demand for long read sequencing grew substantially because of the pandemic. And then of course there are all the new ideas for cancer therapies, which would require long read sequencing. But ...
by Brian4
Fri Jul 29, 2022 7:33 am
Forum: Prevention and Treatment
Topic: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)
Replies: 25
Views: 3659

Re: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)

So sorry about the COVID, my friend — extra scary with the E4s. Please take care of yourself. I have so many friends who felt better, then ultimately overextended themselves for a bigger relapse. Take it slowly. I also think you're onto something with the notion of "illness" causing a red...