Search found 7310 matches

by Julie G
Tue Oct 18, 2022 10:51 am
Forum: Prevention and Treatment
Topic: Sourcing Homotaurine
Replies: 4
Views: 345

Re: Sourcing Homotaurine

Does anyone know of a quality source of homotaurine for experimental use? I'm only aware of https://us.supersmart.com/en/shop/brain-nutrition/homotaurine-supplement-0661. Their certificate of analysis looks rather informal (I don't see any evidence that it was provided by a third party) and it does...
by Julie G
Fri Aug 12, 2022 8:54 am
Forum: Science and Research
Topic: APOLLOE4 Study: Are you or someone you know struggling with memory loss?
Replies: 10
Views: 2557

Re: APOLLOE4 Study: Are you or someone you know struggling with memory loss?

After sharing NF52's comments, the study coordinator provided a bit of clarification.
While this phase of recruitment is winding down, interested individuals can still check in here: https://apolloe4.researchstudytrial.com/ as they may continue to accept new individuals for a while longer.
by Julie G
Thu Aug 11, 2022 7:46 pm
Forum: Science and Research
Topic: APOLLOE4 Study: Are you or someone you know struggling with memory loss?
Replies: 10
Views: 2557

Re: APOLLOE4 Study: Are you or someone you know struggling with memory loss?

Any chance your contact was referring to Phase 2 study, just closed to recruitment. I'd hate our members to lose out on info about a trial exclusively seeking ApoE 4/4 individuals with MCI/mild AD. My contact at Sano Genetics specifically provided the link to this thread on our website and asked me...
by Julie G
Thu Aug 11, 2022 2:56 pm
Forum: Prevention and Treatment
Topic: Prodrome blood test results, initial and over time
Replies: 49
Views: 5497

Re: Prodrome blood test results, initial and over time

Notes on my second ProdromeScan: I’ve had to sit with these results for awhile because the results and the consultation were discouraging... Thank you so much for the thorough recap of your second Prodrome Scan. You actually validated all my thoughts, and concerns, and especially doubts I had after...
by Julie G
Thu Aug 11, 2022 2:32 pm
Forum: Science and Research
Topic: APOLLOE4 Study: Are you or someone you know struggling with memory loss?
Replies: 10
Views: 2557

Re: APOLLOE4 Study: Are you or someone you know struggling with memory loss?

Julie, I think the study that is no longer accepting participants is the the Gene Therapy for APOE4 Homozygote of Alzheimer's Disease... Ah, thank you for the update. I received this note yesterday from my contact at Sano Genetics: I hope you are well. I wanted to reach out today for two reasons. F...
by Julie G
Wed Aug 10, 2022 9:13 am
Forum: Science and Research
Topic: APOLLOE4 Study: Are you or someone you know struggling with memory loss?
Replies: 10
Views: 2557

Re: APOLLOE4 Study: Are you or someone you know struggling with memory loss?

Hi all. This phase of the APOLLOE4 study has concluded. The study organizers have asked me to let you know that this opportunity is no longer available. When/if they have further updates, we'll be happy to share them.
by Julie G
Mon Aug 01, 2022 12:46 pm
Forum: Prevention and Treatment
Topic: Still trying to make sense if it is worth APOE4 to get a vaccine for Shingles and VZV?
Replies: 13
Views: 1052

Re: Still trying to make sense if it is worth APOE4 to get a vaccine for Shingles and VZV?

There has been consistent data coming out that suggest multiple vaccines, including those for shingles, flu, and BCG (tuberculosis) all may protect against dementia. This may help make up your mind: Herpes Zoster Vaccination Reduces Risk of Dementia. Conclusion: Our finding that HZ vaccination reduc...
by Julie G
Sun Jul 31, 2022 6:45 am
Forum: Prevention and Treatment
Topic: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)
Replies: 25
Views: 1495

Re: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)

I think Brian is suggesting the opposite, that increased volumetrics could be the result of inflammation and resolution would result in reduced grey volume. I checked with Dr. Raji and he pointed to this study as an example of Brian’s theory: https://pubmed.ncbi.nlm.nih.gov/24946038/. His comments: ...
by Julie G
Fri Jul 29, 2022 9:29 am
Forum: Prevention and Treatment
Topic: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)
Replies: 25
Views: 1495

Re: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)

By the way, the point the neurologist made was that a decrease in overall gray matter can be a good thing: it can mean that brain inflammation has resolved. Key to interpretation is looking at changes in particular subregions, such as the caudate nucleus. I bet in some cases (depending on the regio...
by Julie G
Thu Jul 28, 2022 1:08 pm
Forum: Prevention and Treatment
Topic: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)
Replies: 25
Views: 1495

Re: Julie's letter to Dr. Hellmuth (& all who've lost scientific curiosity & support status quo in AD research)

So I see some common ground among various views---and I need to step up my step intensity!! Nice sleuthing and me too on the exercise. I love getting in 3.5-4 miles daily, but too often life gets in the way. :? Speaking of inflamed brains, I have COVID-19 (minimal lung involvement, so I'll be fine)...