Search found 2152 matches

by NF52
Thu Jan 30, 2025 1:04 pm
Forum: Our Stories
Topic: Doomscrolling
Replies: 3
Views: 5871

Re: Doomscrolling

I try to convince myself that learning my APOE status (I’m a 4/4) was a blessing in disguise, but then I come across articles like this: https://www.cnn.com/2022/04/05/health/new-alzheimers-genes-wellness/index.html, and I feel like I’m doomed. This particular quote scares me: “Lifestyle factors su...
by NF52
Fri Jan 24, 2025 2:03 pm
Forum: Getting Started
Topic: Welcome!!!
Replies: 352
Views: 437938

Re: Welcome!!!

Thanks for the reply and the welcome. One of my specialties has been is scientific knowledge and medical data curation and organization for precision medicine data, so I really appreciate what you've done here. I was about to embark on pulling together something like this for myself, friends and fa...
by NF52
Thu Jan 23, 2025 5:14 pm
Forum: Getting Started
Topic: Welcome!!!
Replies: 352
Views: 437938

Re: Welcome!!!

Hi Stavia, I just joined today. I'm a scientist by training (PhD, cell & molecular biology). I'm grateful to find a forum like this one after discovering that I'm an APOE4 carrier. I had the same question as the user below about 23&Me. I poked around on the site and figured out how to deter...
by NF52
Wed Jan 22, 2025 4:46 pm
Forum: Getting Started
Topic: APOE4 /4 conflicting information
Replies: 23
Views: 15830

Re: APOE4 /4 conflicting information

update! (perhaps naively) I am determined to be the % of APOE4 who may end up with amyloid plaque etc but no clinical symptoms. i am exercising daily, taking care of cholesterol and now sleeping (gummies). i found hope here and really read the report from Spain carefully and the reviews —biological...
by NF52
Tue Jan 21, 2025 11:54 am
Forum: Prevention and Treatment
Topic: Oura ring
Replies: 12
Views: 7944

Re: Oura ring

A little bit of history - the 1st gen commercial HRV monitors were bands placed around the chest and directly over the heart. As the technology improved, watches and wristbands were introduced. Now, the technology has improved and rings have been introduced. With that said, it is highly unlikely th...
by NF52
Mon Jan 20, 2025 6:02 pm
Forum: Prevention and Treatment
Topic: telling spouse of death
Replies: 8
Views: 3945

Re: telling spouse of death

Dad died last night. Mom has had AD for a long time. She knows me and my husband and remembers some things from long ago, but can't remember what she had for breakfast. She is not combative anymore. What is more merciful? To tell her that he died, and then she will have to be reminded over and over...
by NF52
Sun Jan 19, 2025 9:58 pm
Forum: Our Stories
Topic: Apoe 3/4 gene and white matter hyperintensities
Replies: 2
Views: 4932

Re: Apoe 3/4 gene and white matter hyperintensities

I am 48 almost 49. A quick recap of my story: a lifelong migraine sufferer had an MRI where multiple millimetric white matter hyperintensities were found . I have done so much testing and all they found is that I have one copy of the gene. So maybe these lesions came from the gene. I'm scared out o...
by NF52
Sat Jan 18, 2025 5:49 pm
Forum: Getting Started
Topic: New to forum: 4/4 with positive plasma pTau217
Replies: 2
Views: 2809

Re: New to forum: 4/4 with positive plasma pTau217

Hello everyone, Joined forum today. I am 65, 4/4, normal cognition (for now!), got my plasma pTau217 'positive' results yesterday with a value 0.82 (A test result >0.63 ng/L is positive and is consistent with a positive amyloid PET scan with 95% positive predictive value). My neurologist is setting...
by NF52
Tue Jan 07, 2025 4:02 pm
Forum: Our Stories
Topic: Question about Alzheimers smell
Replies: 6
Views: 7432

Re: Question about Alzheimers smell

https://www.sciencefocus.com/the-human-body/what-does-disease-smell-like Another article about different disease smells. Thanks for sharing these! I had forgotten reading about the wife who is a super-smeller and her help to researchers. The classic biomarker of Parkinson’s disease, which that woma...
by NF52
Tue Jan 07, 2025 3:15 pm
Forum: Our Stories
Topic: Question about Alzheimers smell
Replies: 6
Views: 7432

Re: Question about Alzheimers smell

New here bu have been reading some of your discussions for the past few years. My husband (just turned 40) is APOE4x1. His mother lives with us and has had Alzheimers since her early 60s (now 78) her mom had it as well and I think it goes back in the family quite a ways. While I try not to think ab...