An LDL of approximately 70 is great, but not particularly low -- except maybe for an e4.

LDL and apoB are the measurements to pay attention to. Optimal apoB is 40-80, ideally below 62.

I would like to discourage you from attempting to raise either LDL or apoB.

Hi Maria4/4, Thanks for adding this information to the discussion and for providing the link. Have you tried any of these alternatives yourself? Hi Floramaria, I didn’t try them because my cholesterol levels are low. Perhaps even too low 😒 Too low? Care to elaborate? I assume you are not saying tha...

Hi there - so we have a surprise pregnancy (but very much wanted). I am 43 but 44 in 2 weeks. I found out about my 4/4 status approx 4 years ago. I fast most days and take the recommended supplements etc. But i have been lax with my diet. My questions are , will this pregnancy ‘accelerate’ any issu...

This diet is totally the opposit what I should eat according what I found in this forum :( I bearly eat fat There is not just one recommended diet for AD prevention. I am also low fat plant based and it works for me, as evidenced by my A1c, Apob/LDL, and how I feel. Others do a Mediterranean diet o...

Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial Premranjan K...

Hi, I am not new to this website. I have been creeping on the conversations in the forums for some time. I think I am an APOE 4/4? I had my genes mapped with Nebula Genomics and have found it very difficult to understand the website that can confirm my APOE status. Hence my vagueness re my APOE sta...

Thanks, AussieinLA,

I'm intrigued, but is there a way to do this without having to provide our emails? I am tempted to create my own version instead.

This article agrees with BrianR's entry that high HDL may be about metabolic disorder in those over 75, and dementia risk.

Here's a link to the study in Lancet.

Here's a Ted Talk / Ted article on a brain healthy diet, by Lisa Mosconi, Director of the Women's Brain Initiative and associate director of the Alzheimer's Prevention Clinic at Weill Cornell Medicine. Link to the article is below Manage your carbs Get to know the phytoestrogens Protect the brain wi...

Hi all, I just came across this study in JAMA Neurology (not open access, unfortunately), suggesting that slow-wave sleep is critical, especially for e4s over 60. Apoe4 is associated with a greater decline in slow-wave sleep and not enough slow-wave sleep is a modifiable risk factor for AD. Here's a...