This is very informative, thank you Laurie!

One "supplement": Veggies:
https://nutritionfacts.org/video/mitoch ... -of-aging/

Just adding a 2004 study here for more info regarding MTHFR, homocysteine and coffee: "The methylenetetrahydrofolate reductase C677T polymorphism is a major determinant of coffee-induced increase of plasma homocysteine: A randomized placebo controlled study" INTERNATIONAL JOURNAL OF MOLECU...

This is a 2006 study: "Drinking tea is associated with lower plasma total homocysteine in older women" http://apjcn.nhri.org.tw/server/APJCN/15/2/253.pdf In Dr. Neal Barnard's Power Foods for the Brain (2013), page 80, he references the 2010 study finding that those with the APOE e4 allele...

Thank you so much for your thoughts, SusanJ!

Thank you, Circular: Why such a low dose for B6? I feel like I might be missing something. I thought the right amount was about 20mg of P-5-P? SusanJ: Thanks for the info. I plan to take methylfolate 400mg. But I assume I must take methyl B12 with it, right? I assume I can't do Hydroxocobalamin and ...

Thanks, Circular, that's good to hear. May I ask how much methyl you take for each?

Thanks, Slacker.

To add some more confusion to the mix, here's Dr. William Walsh on methylation status and that SNPs in themselves are not enough to determine each person's case. https://www.youtube.com/watch?v=_ljuIdqEa84

Slacker, I was taking folic acid and cyanocobalamin before I knew about my MTHFR mutations and I think they influenced my B levels for my blood tests in November. They were both extremely high. I am now taking hydroxocobalamin and eating folate rich foods--because I don't know whether to take methyl...

I read that a coffee filter made of paper doesn't make a difference (though I have also heard the opposite).