I have read the link on niacin from Mayo Clinic but am hesitant to put much weight to it because many of the studies regarding Niacin that I have seen are in combination with a statin, and time-released Niacin. I also believe that keeping cholesterol naturally low (without statins) as a result of di...

I have not been able to find anything that gives me a clear answer regarding what the target values are for E4's to help prevent AD. I just had my cholesterol checked and total is 180, with HDL 65 and LDL 97 (I need to push that down more). My triglycerides are 89, Homocysteine 8.5....working on pus...

This is an interesting topic that I researched over a year before I found out about my 4/4 status. My husband (who is homozygous for the MTHFR gene variant) had a high coronary calcium score. Cardiologist wanted him on statins, but I did a lot of research on pubmed and found the studies about pomegr...

I went through TM instruction (Transcendental Meditation) some 25 years ago, think I paid hundreds of dollars at the time... and while I have not meditated on a very regular basis, I have always used this technique when I have had a bad night sleep and needed to be fit the next day. I'd meditate for...

particularly for me, 4/4 and very Type A....always on the go, I recognize that this is an important aspect of my prevention regiment.
I've just started and found it very grounding.

Another no-cost possible prevention method: https://agelessartsyoga.com/instructor- ... meditation

was the B Complex methyl? In addition to being 4/4, I also have an MTHFR defect (C677T) which impairs my methylation cycle up to 80%. My homocysteine was high (12.7) but I also brought it down to 7.2 with METHYL B Complex. If I took standard B Complex with folic acid and cyanocobalamin, my homocyste...

Since finding out my 4/4 status earlier this year, I have been on an emotional roller coaster. While I have moments of being ok, I am deeply disturbed and freaked out by the prospect of losing my sanity and the essence of ME. The statistics I found, initially were something like 60% of APOE4 had AD ...

Just saw this news article....it sounds rather promising that a vaccine could be on the horizon....https://alzres.biomedcentral.com/articl ... 018-0441-4

I have started supplementing with this as recommended in Dr. Bredesen's book. Anyone else trying it? It sounds like a very worthwhile supplement to me. Be aware that the available strengths vary.... 4mg, 12 mg......and I'm sure others. In any event, it looks to be neuro-protective and at this point,...