Search found 1925 matches

by NF52
Fri Jan 19, 2024 6:16 am
Forum: Prevention and Treatment
Topic: CT contrast
Replies: 4
Views: 967

Re: CT contrast

Does anyone know anything about CT contrast in regards to brain health? I’m supposed to have a CT w/contrast, and I’m concerned. It looks like it will be oral and IV contrast. Not happy. Thanks for any light you can shed :) Hi QueenJane! Your question is timely, since someone else asked the same th...
by NF52
Wed Jan 17, 2024 1:00 pm
Forum: Prevention and Treatment
Topic: Genetic Testing for PSEN1, PSEN2, APP
Replies: 5
Views: 840

Re: Genetic Testing for PSEN1, PSEN2, APP

Hello I’m sure this has been asked before, but I’m wondering if there is a resource for genetic testing of PSEN1, PSEN2, APP without going through a Dr? The men in my mom’s family line have all started showing impairment in their late forties through sixty. I’m a very healthy 50, and I want to know...
by NF52
Wed Jan 17, 2024 10:22 am
Forum: Announcements and Events
Topic: National Academy Research WS for preventing and treatment of AD
Replies: 2
Views: 507

Re: National Academy Research WS for preventing and treatment of AD

Here's the link to register: It began today 1/16/24 thru 1/17/24- https://www.nationalacademies.org/event/41563_01-2024_research-priorities-for-preventing-and-treating-alzheimers-disease-and-related-dementias-january-workshop?utm_source=NASEM+News+and+Publications&utm_campaign=d4939c905c-EMAIL_...
by NF52
Wed Jan 17, 2024 8:00 am
Forum: Announcements and Events
Topic: National Academy Research WS for preventing and treatment of AD
Replies: 2
Views: 507

Re: National Academy Research WS for preventing and treatment of AD

Here's the link to register: It began today 1/16/24 thru 1/17/24- https://www.nationalacademies.org/event/41563_01-2024_research-priorities-for-preventing-and-treating-alzheimers-disease-and-related-dementias-january-workshop?utm_source=NASEM+News+and+Publications&utm_campaign=d4939c905c-EMAIL_...
by NF52
Wed Jan 17, 2024 7:14 am
Forum: Our Stories
Topic: Greetings from a cold northern Europe
Replies: 7
Views: 1207

Re: Greetings from a cold northern Europe

I'm a 65 years old male with Alzheimer's. I was forced to retire two years ago, due to memory problems and got my official diagnosis 4,5 years ago. My grandmother and father had Alzheimer's so there seems to be a strong genetic component. At some point I was obsessed with genetics and got a full ge...
by NF52
Sat Jan 13, 2024 11:00 am
Forum: Announcements and Events
Topic: New Study. FN1 modifiers and APOE4
Replies: 12
Views: 12434

Re: New Study. FN1 modifiers and APOE4

Thank you for the response. This is all so fascinating. Reading these studies can be mind-numbing. Is it your understanding that rs116558455 is common in the sense that just about everyone has it and that the variant G is the one found 99+% of the time? Or is rs116558455 a rare mutation regardless ...
by NF52
Sat Jan 13, 2024 10:15 am
Forum: Prevention and Treatment
Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
Replies: 1808
Views: 346369

Re: Celebration Thread! Biogen is going to the FDA with Aducan.

NF52, this is another exciting development that you have mentioned about the AHEAD study. In the above figure the red line is where mab treatment needs to start for 95% disease slowing to occur. What you have noted is that if patients progress into early MCI while in AHEAD then they will be transfe...
by NF52
Fri Jan 12, 2024 6:00 pm
Forum: Prevention and Treatment
Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
Replies: 1808
Views: 346369

Re: Celebration Thread! Biogen is going to the FDA with Aducan.

I learned of this at my most recent infusion; not every person in the trial has even been notified yet since it is a December revision in the IRB consent. Thanks for sharing these updates, NF52. I imagine that this will skew the numbers in the original dataset if enough people drop out of the contr...
by NF52
Thu Jan 11, 2024 12:03 pm
Forum: Announcements and Events
Topic: New Study. FN1 modifiers and APOE4
Replies: 12
Views: 12434

Re: New Study. FN1 modifiers and APOE4

Louise Gray wrote: Thu Jan 11, 2024 11:44 am I don’t think rs116558455 is genotyped on 23andme
So that new chip won't give me that info, but I did find the frequency on an NIH site, in case some have done whole genome sequencing. Thanks for sharing!
by NF52
Thu Jan 11, 2024 7:56 am
Forum: Our Stories
Topic: 59 yo, 4/4, and brain full of plaque
Replies: 7
Views: 13079

Re: 59 yo, 4/4, and brain full of plaque

Thank you for the replies. I’m very surprised there is someone with a story so similar to mine! glampers I’ll private message you. The Ahead study told me I had “more than some” plaque which qualified me for the group that would receive the infusion every two weeks. I guess I didn’t ask them to be ...