Search found 298 matches

by BrianR
Sun Dec 30, 2018 7:42 am
Forum: Science and Research
Topic: Long-term intake of vegetables and fruits and subjective cognitive function in US men
Replies: 1
Views: 1227

Long-term intake of vegetables and fruits and subjective cognitive function in US men

Long-term intake of vegetables and fruits and subjective cognitive function in US men Changzheng Yuan, Elinor Fondell, Ambika Bhushan, Alberto Ascherio, Olivia I. Okereke, Francine Grodstein, Walter C. Willett First published November 21, 2018, DOI: https://doi.org/10.1212/WNL.0000000000006684 Not ...
by BrianR
Mon Dec 24, 2018 11:21 am
Forum: Prevention and Treatment
Topic: article: Iron Is the New Cholesterol
Replies: 3
Views: 2825

article: Iron Is the New Cholesterol

I enjoyed this new article at Nautilus: Iron Is the New Cholesterol . A bit from the section that discussed AD: Perhaps most surprising was the discovery in 1999 that the pre-cursor to amyloid-b was under direct control by cellular iron levels—the more iron around, the more amyloid was produced.41 T...
by BrianR
Fri Dec 21, 2018 5:12 pm
Forum: Science and Research
Topic: apoe4 and osteoporosis.
Replies: 19
Views: 7179

Re: apoe4 and osteoporosis.

I have had good luck over the past few months with Sci-Hub's Taiwan address, http://sci-hub.tw. I believe a search for 10.1301/nr.2003.apr.132-135 will do the trick. :-) I recommend the Where is Sci-Hub now? website. In theory, the following link should always point to a usable Sci-Hub link: https:...
by BrianR
Thu Dec 20, 2018 12:35 pm
Forum: Science and Research
Topic: New Alzheimer’s treatment fully restores memory function
Replies: 7
Views: 3480

Re: New Alzheimer’s treatment fully restores memory function

The Australian Department of Health announced $10 million in funding for a clinical study aimed at opening "the blood-brain barrier enabling the clearance of toxic protein plaques from the brain": https://www.uq.edu.au/news/article/2018/12/new-funding-takes-uq-towards-clinical-trials-of-de...
by BrianR
Tue Dec 18, 2018 4:40 pm
Forum: Science and Research
Topic: Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease
Replies: 7
Views: 2395

Re: Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease

Was just reading and corresponding with some folks doing research in this area. While I don't know much about this particular study - except that the authors have / are patenting some small molecules - I have thought this avenue of research is the most promising I've seen in a while! I found it par...
by BrianR
Tue Dec 18, 2018 4:21 pm
Forum: Our Stories
Topic: mTOR, metformin, and tendonitis?
Replies: 1
Views: 1488

Re: mTOR, metformin, and tendonitis?

... Have any of ya'll experienced problems like this? Is it a big mistake to continue with metformin while on ketogenic diet? I have seen some comments about mTOR cycling in these forums, but sis not see any follow up on that. Thanks. Hi Whatnow. Rhonda Patrick just sent out a reference to this pap...
by BrianR
Mon Dec 17, 2018 4:55 pm
Forum: Science and Research
Topic: Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease
Replies: 7
Views: 2395

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease

new paper: Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease https://elifesciences.org/articles/40048 Xunde Xian Is a corresponding author , Theresa Pohlkamp, Murat S Durakoglugil, Connie H Wong, Jürgen K Beck, Courtney Lane-Donovan, Florian Plattner, J...
by BrianR
Thu Nov 22, 2018 4:21 pm
Forum: Science and Research
Topic: Slowed brainwaves linked to early signs of brain cells going haywire due to dementia
Replies: 1
Views: 1209

Slowed brainwaves linked to early signs of brain cells going haywire due to dementia

From Science News: Slowed brainwaves linked to early signs of brain cells going haywire due to dementia The study [ see below ], published online in the journal, Human Brain Mapping, found that individuals potentially in the early stages of Alzheimer's disease ... exhibited sluggish brainwaves and s...
by BrianR
Thu Nov 22, 2018 1:10 pm
Forum: Science and Research
Topic: podcast: microbiologists discuss HSV causing AD hypothesis
Replies: 0
Views: 849

podcast: microbiologists discuss HSV causing AD hypothesis

The This Week In Virology Episode 519 podcast has a discussion: "The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer’s Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles." The HSV/AD content starts a...