Search found 2551 matches

by SusanJ
Sun Jan 15, 2023 9:48 am
Forum: Prevention and Treatment
Topic: Any thoughts on lecithin (phosphatidylcholine)?
Replies: 20
Views: 4881

Re: Any thoughts on lecithin (phosphatidylcholine)?

This issue is probably more nuanced than choline = TMA = heart disease. I posted this article in another thread, but thought it would be useful to this discussion. Bottom line with any associative study is we don't understand what folks are eating besides meat or eggs (or anything else for that matt...
by SusanJ
Sun Jan 15, 2023 9:22 am
Forum: Prevention and Treatment
Topic: Hormone Replacement Therapy E4 Women
Replies: 773
Views: 325562

Re: Hormone Replacement Therapy E4 Women

Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of Alzheimer’s Disease (EPAD) cohort The study shows that HRT use is associated with better memory, cognition and larger brain volumes in later lif...
by SusanJ
Sat Jan 14, 2023 10:30 am
Forum: Prevention and Treatment
Topic: How to test and solve oral bacteria issues
Replies: 19
Views: 6543

Re: How to test and solve oral bacteria issues

Erythritol Functional Roles in Oral-Systemic Health Oral health studies revealed that erythritol can reduce dental plaque weight, reduce dental plaque acids, reduce counts of mutans streptococci in saliva and dental plaque, and reduce the risk for dental caries better than sorbitol and xylitol, res...
by SusanJ
Mon Jan 09, 2023 5:22 pm
Forum: Science and Research
Topic: Very Good Peter Attia podcast
Replies: 16
Views: 10532

Re: Very Good Peter Attia podcast

When you say "minor allele" are you saying that "G" is the non-protective version that is usually associated with ApoE4? The paper I cited earlier in this thread said "G" increases the risk. Sorry, we all hope to win the genetic lottery to modify E4 effects, but someti...
by SusanJ
Sun Jan 08, 2023 5:36 pm
Forum: Science and Research
Topic: Very Good Peter Attia podcast
Replies: 16
Views: 10532

Re: Very Good Peter Attia podcast

adriana268 wrote:do you mean you saw a status if tomm40 on your old 23 and me report ?
It's not in any reports. You have to click the "Browse Raw Data" in the dropdown menu under your name. Then put rs2075650 in the search box and read the results. "G" is the minor allele.
by SusanJ
Sun Jan 08, 2023 9:40 am
Forum: Science and Research
Topic: Transposable elements, aka "Jumping genes" a trigger in brain inflammation
Replies: 0
Views: 242

Transposable elements, aka "Jumping genes" a trigger in brain inflammation

Beyond viral infection as a trigger to Alzheimers, we now may also have "jumping genes." Alzheimer's disease and progressive supranuclear palsy are marked by toxic deposits of a protein called tau. Their research found that tau-induced "jumping genes" -- which can relocate or cop...
by SusanJ
Sun Jan 08, 2023 9:22 am
Forum: Prevention and Treatment
Topic: Prodrome blood test results, initial and over time
Replies: 60
Views: 22216

Re: Prodrome blood test results, initial and over time

Do you know the advantages of taking Citicoline versus Phosphatidylcholine? I think it depends on what your goals are. Choline gets metabolized differently depending on your body's needs. For example, I'm post-menopausal and have PEMT variants that suggest that Phosphatidylcholine (skipping the PEM...
by SusanJ
Sat Jan 07, 2023 11:59 am
Forum: Our Stories
Topic: My year of anxiety and insomnia
Replies: 3
Views: 469

Re: My year of anxiety and insomnia

Chrisweides wrote:You could maybe pm me. I feel I need to go to the doctor armed with knowledge.
I will message you with some info.
by SusanJ
Fri Jan 06, 2023 8:37 pm
Forum: Science and Research
Topic: Very Good Peter Attia podcast
Replies: 16
Views: 10532

Re: Very Good Peter Attia podcast

Do you know if these additional snips are reported in 23 and Me? I did not listen to the podcast, but here is a recent research article about those genes. From: Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk (2022) We report the remarkably high excesses of the AD risk for ca...
by SusanJ
Fri Jan 06, 2023 8:22 pm
Forum: Our Stories
Topic: My year of anxiety and insomnia
Replies: 3
Views: 469

Re: My year of anxiety and insomnia

Sadly, either mental illness (depression and anxiety) which I am suffering from for many years or perimenopause or my hashimotos has gotten the best of me last year and I have had the most terrible year of my life. I am so sorry that you've had a terrible year. Hugs to you. If I might make a sugges...