A GWAS Study identifies new risk loci for Alzheimer’s disease

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BrianR
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A GWAS Study identifies new risk loci for Alzheimer’s disease

Postby BrianR » Wed Sep 08, 2021 5:22 pm

A brief summary. Open access:

https://www.nature.com/articles/s41588-021-00921-z.epdf?sharing_token=4akiS2tGVg92pQL1K6H9JNRgN0jAjWel9jnR3ZoTv0Mp8QR0zYEql-oZczk4yfLdXRZVexLAmVmKckOA5AYJm4XlK5vpwVqu9ffoEHjJsppUxdoc9cKSg_5YMvMP8ih1gMbjMThbubmUKRx52ZPBM7S3HzrBRnawzOwrUfd9oCw%3D

A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
Nature Genetics | VOL 53 | SEPTEMBER 2021 | 1276–1282 |
DOI: 10.1038/s41588-021-00921-z


This research appears to be focused on those of northwest European ancestry. (Because that's where the data is.) As I understand their paper, these results appear to be more of a building block to construct a better model for risk assessment and potential genetic targets for medication than a basis for action.
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BenF
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Re: A GWAS Study identifies new risk loci for Alzheimer’s disease

Postby BenF » Mon Sep 13, 2021 12:23 pm

Think I need to download the supplementary info, read more carefully and/or put some of these into snpedia. Not sure on any of the affect sizes or the reliability of the samples. Looks like there’s a wealth of info here.


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