Thanks for this additional information frankiesfriend. I wouldn't have know to ask about the Indica strain specifically. I found a local dispensary where I can get products for sleep. Here are my notes from my call with them. I started by asking what he would recommend and then asking questions as they came up. I haven't done any of my own research to corroborate anything he said:frankiesfriend wrote: ↑Thu Jan 13, 2022 7:29 am I was taking about 5-6 drops of a formulation of 40 mg/ml THC, yielding about 4 mg THC with less than 0.4 mg CBD of the indica strain. I was already taking it when I listened to an interview with Dr. Mikhail Kogan regarding his extensive recommendations of medical marijuana in his medical practice for all kinds of conditions. I ordered his book, but have leant it to a friend so I don't have his specific recommendations in front of me. I did read either in his book or in some scientific studies of the impact of THC and CBD on sleep that CBD in small amounts is stimulatory and that it requires large amounts (which are expensive) if using CBD for sleep. However, THC is sleep inducing in small amounts. Once again, I think it is important to use the indica strain and start with a low dose.
I took it at bedtime along with a 2mg extended release melatonin formulation, which I still take. I would awaken one time each night for a trip to the bathroom and then go right back to sleep until morning. If taking a small dose, I had no sense of being high or unsteady.
In Florida, one must get a state license and see a medical marijuana doctor. It costs around $300, and requires two visits/year to the doctor to continue the prescription. With the license in hand, one can go into a medical marijuana dispensary and buy any amount of anything, no questions asked, even products that are clearly designed to induce a high. The "Budspersons" - not the doctors - guide you in selection of your product. There are gummies, tinctures, oils and smokables. In Florida, there is no legal way to sample any of these products, but I hope that in your state, you can find a way to do that!
I think I'm going to try these edibles and not worry about a little bit of sugar an hour before bed.There's another cannibanoid called CBN isolate with a lot of research on efficacy for sleep.
Wyld makes an edible with it. There is THC and CBD and CBN (In 10 piece package: 100 mg THC, 100 mg CBD, 100 mg CBN)
CBD calms nerves and quiets mind
CBN helps with the restorative sleep cycles
THC helps relax the muscles and promote blood flow and quiets the mind
Interestingly, the guy I was talking to is also sometimes hungry during the night. He said there's a small chance that these formulations could excite appetite, but you (or at least he) will sleep through it and then wake up ravenous. The hunger doesn't last through the day though. In other words, when you're sleeping more deeply the hunger doesn't wake you up.
It has sugar, minute dose, start with 1/2 a piece which is 5 mg.
$25 after taxes for 10 pieces (20 if you stay with a 1/2 dose). Odds of a resistance is very low for many months. "Tolerance" can happen with a long term regimen.
Does it affect hormones? Not that they're currently aware of. For him, it calms and levels moods, but if you take too much it can cause an anxiety attack. At the dose in the Wyld product for sleep above it won't do that.
Does the Wyld product have Indica THC? It is. Indica molecule is very sedative. It attaches to the CB1 and CB2 receptors. The receptors are like a V and the THC is like a triangle, so it's a perfect fit. However, to avoid the psychoactive effects, the CBD is added to block some of the same receptors. CBD is shaped like a circle and it sits inside the receptor and prevents other things from binding to it so it blocks the high feeling of the THC.
Is there a concentrate option? Yes. Indica 300 mg bottle or 600 mg bottle. 1/4 drop is 10-15 mg dose which is average for a tincture. Sublingually takes effect a lot faster. You'd get more THC without it being muted by the CBD. They also have 1:1 mixtures of THC and CBD. He considers this the next step if I don't want to use edibles.
It's interesting that he doesn't seem to think the CBD is stimulatory in these amounts when combined with THC or THC and CBN. This may be better evaluated by individual experimentation.