Sesamol

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Lulu
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Sesamol

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Very interesting study showing benefits for brain and gut health from Sesamol, a ligand from sesame seeds.

Sesamol Attenuates Amyloid Peptide Accumulation and Cognitive Deficits in APP/PS1 Mice: The Mediating Role of the Gut–Brain Axis

https://pubs.acs.org/doi/10.1021/acs.jafc.1c04687
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TheresaB
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Re: Sesamol

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Lulu wrote: Mon Dec 05, 2022 8:33 am Very interesting study showing benefits for brain and gut health from Sesamol, a ligand from sesame seeds.

Sesamol Attenuates Amyloid Peptide Accumulation and Cognitive Deficits in APP/PS1 Mice: The Mediating Role of the Gut–Brain Axis

https://pubs.acs.org/doi/10.1021/acs.jafc.1c04687
If this study interests you, have you read our wiki article Beneficial (and some negative) Plant/Natural Chemicals https://wiki.apoe4.info/wiki/Beneficial ... _Chemicals
There are natural compounds with similar to better results and those results are not from mice studies.
-Theresa
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Lulu
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Re: Sesamol

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Thanks, Theresa, looks like a lot of good information, I'll have enough reading to keep me busy for a while, very helpful :-) From my previous posts, you can see my focus and interest right now is mostly on fiber / pro and pre biotics / the gut -brain axis, and anything that helps contribute to the health of the microbiome. The article and information on sesamol is exciting to me, even if it's just a mice study. Wanted to share, since it could be something new and helpful to the Apoe4 community.

Have you heard of the book, Fiber Fueled by Will Bulsiewicz, MD, MSCI ? I'm just starting to get into it, very interesting as well.
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Re: Sesamol

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Lulu wrote: Mon Dec 05, 2022 10:09 am Thanks, Theresa, looks like a lot of good information, I'll have enough reading to keep me busy for a while, very helpful From my previous posts, you can see my focus and interest right now is mostly on fiber / pro and pre biotics / the gut -brain axis, and anything that helps contribute to the health of the microbiome. The article and information on sesamol is exciting to me, even if it's just a mice study. Wanted to share, since it could be something new and helpful to the Apoe4 community.
Yes! The gut microbiome is so very important. I hear you about having too much to read and not enough time, but did you know we have a wiki on the microbiome too?
Gut-Brain Connection: Leaky Gut/Leaky Brain, Microbiome (gut bugs)
https://wiki.apoe4.info/wiki/Gut-Brain_ ... (gut_bugs)
-Theresa
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Lulu
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Re: Sesamol

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Awesome! I'll dig into that too :-) Thank you
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