Hi Floramaria and Quantifier,floramaria wrote: ↑Tue Sep 06, 2022 8:52 pmThanks for the info on Citicoline and TMAO, Quantifier. Though I could, I don’t want to get all of my choline in supplement form. I prefer eating choline rich foods and supplementing with citicoline. When I did the Chris Masterjohn choline calculator, based on my genetics, to get enough choline I’d need to eat eight egg yolks ( or equivalent) a day.
For now,I’m trying to interrupt the TMA pathway in my microbiome; I have my garlic standing by after eating two eggs on my dinner salad. And popping a resveretrol.
I take Phosphatidylcholine and try to eat eggs regularly, so I was also a little bit worried about TMAO, but I found an article about a new study that is very interesting for us.
"Ten years ago, researchers at The Cleveland Clinic published one of the first studies proposing a link between TMAO, dietary choline, and cardiovascular disease risk,5 but have just published a new study that offers some important new information about choline from eggs, one of the best food sources of choline available. The new study published in The American Journal of Medicine explored the difference between consuming eggs, a whole food source of choline, and taking supplemental choline on TMAO production, and concluded “… it may be more prudent to recommend natural sources of choline, like eggs, over supplements.”6
In this (new) study of healthy adults, TMAO concentrations increased from baseline to end-of-study in the participants who consumed a choline bitartrate supplement alone or in combination with whole eggs or egg whites; however, there was no change in TMAO concentrations in the participants who consumed eggs alone or for those who took supplement of phosphatidylcholine, a form of choline found in eggs."
Link to the article: https://www.incredibleegg.org/articles/ ... -eggs-tmao
I think this is good news
Do you know the advantages of taking Citicoline versus Phosphatidylcholine?