Hi Sandy,sandyt wrote: ↑Tue Dec 20, 2022 7:58 am Does anyone know what the current evidence is on using estriol vs estradiol cream. My doctor has prescribed an estriol/testosterone combo cream for me from the start. But in my search of studies for brain, bone, and cardiovascular health it seems they always use estradiol. I am trying to get some research done before I go back to see the doctor in about 2 weeks. Should I request a switch to estradiol? I would be grateful for any info
I just found your post about estriol. I have the same doubts.
I am using a patch with 0,05mg of estradiol and I take 100mg of progesterone and I feel fine (all my menopausal symptoms have disappeared). With this dose I am able to have the Estradiol minimum levels required in the Bredesen protocol.
Recently I started seeing a functional medicine doctor and she prescribed 0,5mg estradiol (10 times more than I am taking) and also 2mg estriol. This would be a huge increase in my estrogen intake, so I didn't ordered it to the pharmacy and continued to use the estradiol patch. I am afraid to get cancer with so much estrogen.
I read this thread several times and discovered this usefull information:
E2 (estradiol) receptors in brain, not E3 (estriol)
E3 good for atrophic vaginitis and urinary issues
when older women with breast cancer were treated with estriol, 25% had increased growth of metastases. Overall, his experiments led him to conclude that continuous estriol was not an effective therapy for breast cancer in women. Thus, the "safer" theory of estriol therapy over estradiol and estrone with regard to breast cancer prevention in postmenopausal women has not been established. http://www.medscape.com/viewarticle/571299_3
Honestly I'm confused. I don't know why my doctor prescribed this huge amount of estriol. I talked with some of my friends that are on HRT and they all take estriol + estradiol (it seems that the functional medicine doctors here are all prescribing this combination).
Were you able to find out more information about this theme?
Thanks a lot,