NIA to fund ApoE testing & fluid-based biomarkers for current trials

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NF52
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NIA to fund ApoE testing & fluid-based biomarkers for current trials

Post by NF52 »

The National Institute for Neurological Disorders and Stroke (NINDS), which along with the National Institute on Aging (NIA) is part of the NIH and funds major pharmacological and non-pharmacological human and animal AD research, has issued a new grant to add ApoE genotyping and blood-based biomarkers to current human-subject trials funded by NINDS grants. This is likely to benefit the ApoE 4 field as grant-seekers realize that the NIA and NINDS want these included in their research. This supplement to existing grants could add greatly to the database for both pre-symptomatic and symptomatic Alzheimer's pathology in ApoE 4 carriers.

Here's the goal:
The purpose of this one-year administrative supplement is to provide support for currently active NINDS Alzheimer’s Disease and Alzheimer’s Disease Related Dementias (AD/ADRD) awards to add/include APOE genotype and fluid-based AD/ADRD biomarkers to ongoing AD/ADRD human subjects research studies and generate new data that should enhance the clinical and scientific content of the study, now and in the future via data sharing....

In 2022, the NINDS led ADRD Summit resulted in ADRD research priorities, including multiple milestones that address the need to better understand AD/ADRD risk, assessment, diagnosis, detection, target engagement, monitoring and patient stratification through use of biomarkers. Recently, advances in fluid-based biomarkers for AD/ADRD offer the opportunity to generate new data for AD/ADRD human subjects research projects. It is hoped that these additional AD/ADRD biomarkers will directly benefit the science of the ongoing project as well as enhance the long-term impact of the research. An important outcome of this program will be to increase the diversity of populations for which the selected biomarkers have been assessed.
Administrative Supplement Program to Add Fluid-based Biomarkers and APOE Genotyping to NINDS ADRD Human Subjects Research Grantsl
4/4 and still an optimist!
circular
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Re: NIA to fund ApoE testing & fluid-based biomarkers for current trials

Post by circular »

Nice!
ApoE 3/4 > Thanks in advance for any responses made to my posts.
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