Hello Pacha4rL9!,Pacha4rL9! wrote: ↑Sun Sep 22, 2024 2:36 pm I am new to this site and am very appreciative of all the comments about Quest and Abeta 42/40 because I just got my results from them with a good PTAU and the ABETA in RED!
ABETA 40
208 pg/mL See Note 1
ABETA 42/40 RATIO
0.144 L
Reference Range: > OR = 0.170
Plasma beta-amyloid 42/40 ratio Risk Table:
Risk of Alzheimer's Disease:
Lower Risk: > or = 0.170
Intermediate Risk: 0.150 - 0.169
Higher Risk: <0.150
The concentrations on this report only represent wild type
Abeta 40 and 42. The variants of Abeta 40 and 42 are not
detected in this assay.
QUEST AD DETECT PTAU217, PLASMA 0.07
Reference Range: < OR = 0.15pg/mL
Normal or low plasma p-tau217 levels are inconsistent with
mild cognitive impairment and dementia due to Alzheimer's
disease.
QUEST AD DETECT PTAU181, PLASMA 0.86
Reference Range: < OR = 1.07pg/mL
Normal or low Plasma p-tau181 levels are inconsistent with
MCI and dementia due to Alzheimer's disease.
My name is Laurie and I am a Support Team Intern, and would like to welcome you to this site! You have found a very informative, supportive and encouraging community here, and I am so glad you are already enjoying all the comments. Please continue to look around and see all the resources we have to offer.
Take a look through these links below, I am sure you will find even more helpful and supportive information:
We would love to hear more of your own story, and what brought you to this site, when you feel comfortable. You can post that as a reply here, or in the "Our Stories" section. You might want to read through other members' experiences in Our Stories. Sometimes reading the stories of others helps us realize that we are not alone.
If you haven't already, it would be a great idea to also take a look at our Primer. It is an incredible resource of information about the biochemistry of ApoE4. It offers researched-based prevention strategies and was written by a practicing M.D. with ApoE4. Do not become overwhelmed with all the information. Sometimes it is best to slowly read through it, decide which section resonates with you, and focus on that area first.
The How-To Guide will help you learn how to navigate this site. It includes topics such as navigating the forum, private messaging, and searching.
You certainly have an incredible amount of knowledge and information regarding your health and lab markers. Clearly you are digging deep and finding out all you can to help yourself. You may also find this article helpful.
https://pennmemorycenter.org/new-ad-blood-test/
The article notes that the Quest test has never been used in large clinical trials, unlike other tests where blood test results were confirmed using PET scan on 1000's of people with normal cognition or memory concerns. Up to 29% of people who are told that they are at "high risk" from the Quest test are actually getting a "false positive". That means that the test is not highly accurate. Someone could be told they are "high risk" and actually have levels of amyloid plaques that are low enough to be considered "negative" on a PET scan. In contrast, other blood tests such as PrecivityAD2™ have about an 85% accuracy for people who have no memory concerns, and about 95% for people with MCI who do have Alzheimer's disease.
In closing we want to encourage you to continue your research and knowledge, knowing that there is so much you can do to prevent, halt and even possibly reverse any changes you may already be noticing.
We are so glad you have joined us on this site. Please feel free to reach out anytime with questions or if you just need support. You are not alone. We are here for you.
Kindly,
Laurie Sotro
Support Team Intern
