Book: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's

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TheresaB
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Book: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's

Post by TheresaB »

I thought I'd inform on a book that may be of interest to some. This Tuesday, February 4th, the book, Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's by Charles Piller will be released. Charles Piller is an investigative journalist for Science magazine.
Doctored.jpg
Some may remember Charles Piller for his article, Blots on a Field where he revealed fraud by way of doctored images in a 2006 paper which heavily influenced Alzheimer's research along the amyloid hypothesis. Blots on a Field was published in 2022 and in July of last year the original paper was finally retracted, but only after a great deal of money and research followed the findings of that flawed paper.

This book covers that and more. From the description on Amazon - Doctored
Nearly seven million Americans live with Alzheimer’s disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller’s Doctored shows that we’ve quite likely been walking the wrong path to finding a cure all along—led astray by a cabal of self-interested researchers, government accomplices, and corporate greed.

Piller begins with a whistleblower—Vanderbilt professor Matthew Schrag—whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize–rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Piller’s revelations of Schrag’s findings stunned the field and the public.

From there, based on years of investigative reporting, this “seminal account of deceit that will long be remembered” (Katherine Eban, author of Bottle of Lies and Vanity Fair special correspondent) exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimer’s research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field’s institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimer’s disease, but for scientific research, funding, and oversight at large.
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-Theresa
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