Welcome, Aerwyk!AerwykF wrote: ↑Sat Apr 02, 2022 2:18 pm A pity this particular conversation died or went into hibernation. I spend an inordinate amount of time reading NIH records of almost anything to do with dementia....
The NIH library has erupted with light and audio technique studies. All that I have read has been quite positive. One thing though, don't try to use both simultaneously
unless you have a way to synchronize them. Trying to eyeball them doesn't work.
Sorry this is a bit of a ramble and stream of thought. I'm 84 and I'm tired in spite of the fact I don't look or act like it. Does anyone have anything they'd like to contribute to this discussion? Oh, in addition to the NIH, I spend a lot of time here.
Good health to all.....
Thank you for posting and reminding us that just because studies are not in the media every day, or on this forum, does not mean that great work isn't being done to deepen and broaden our understanding of how to prevent, delay, slow down or even reverse cognitive impairments using multiple modalities. Like you, I spend both a lot of time here and a lot of time trying to stay at least somewhat familiar with studies--although I've learned that it's a lot easier to "cure" mice than people!
I thought I'd share a source I've found useful, in addition to the NIH and the National Institute on Aging (NIA):
describes itself as
I like their weekly newsletter, which often includes breaking research or discussion of current areas of controversy, with comments from leaders in the field.a news website and information resource dedicated to helping researchers accelerate discovery and advance development of diagnostics and treatments for Alzheimer’s disease and related disorders.
Our site expands the traditional mode of scientific communication by reporting the latest scientific findings and industry news with insightful analysis that puts breaking news into context.... Alzforum is a platform to disseminate the evolving knowledge around basic, translational, and clinical research in the field of AD.
Alzforum is supported by a team with backgrounds in science journalism, information technology, design, and data science. Together with a distinguished Scientific Advisory Board, and the active participation of a global network of scientists, we strive to produce unbiased content to a rigorous editorial standard.... Alzforum does not endorse any specific product or scientific approach.
And here's a 2021 compilation of nutrition advice for those with ApoE4 from a groups that includes Dr. Richard Isaacson, Director of Alzheimer’s Prevention Clinic at Weill Cornell Medical Center in New York City. No one has the claim to perfect understanding, but as someone with two copies of ApoE 4 and a little more than a decade younger than you, I found the suggestions helpful and the explanations readable, especially the summaries on pp. 14-15: Precision Nutrition for Alzheimer’s Prevention in ApoE4 Carriers
If I can share a bit more, I've had the privilege of working with great researchers as a Consumer Reviewer of grants and as a member of a Clinical Trial Participant Advisory Board. One of the surprising and somewhat encouraging findings I hear consistently is that what we call "Alzheimer's" in those over age 80 is almost always "mixed dementia" in which the person may have some of the amyloid plaques and tau tangles of Alzheimer's, but also has some features of blood-brain barrier leakage and vascular disease. The reason this may be somewhat encouraging is that it also seems that these diseases progress more slowly and unevenly at this age--similar to how cancers sometimes appear indolent or slow-progressing at this age.
My own mother had at least one copy of ApoE4 and developed mild cognitive impairment in her late 70's, but progressed to only moderate dementia by the time she died of heart failure at age 86. She was able to live in her own home with support and maintained her lifelong sweet personality. Each journey with these disease is unique; what is not is the importance of care partners like you, who have to manage the sadness of losing a spouse in moments over years, not all at once. I also know that she would want you to reach out to friends, families and that doctor you trust for what you need to care for yourself also. You are brave to admit that you're tired--I hope you are also ready to find ways to re-charge yourself.