To my knowledge, this is the first clinical trial that has shown improvement for those with early-stage dementia. You can read it here: Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project.
This is very exciting for those of us using a personalized approach to optimize cognition. Despite the fact that the trial occurred during the worst of COVID (a huge confounder), 84% of patients were able to improve cognition. Not only were cognitive scores improved, but brain imaging was as well.
Dr. Bredesen already has a larger randomized controlled trial underway with sites in Miami, Cleveland, Nashville, Sacramento, and the San Francisco Bay Area. Onwards and upwards!
Dr. Bredesen's clinical trial is published in JAD
Dr. Bredesen's clinical trial is published in JAD
You do not have the required permissions to view the files attached to this post.
Re: Dr. Bredesen's clinical trial is published in JAD
Very promising, but wondering why so few 4/4s...
Sonoma Mike
4/4
4/4
Re: Dr. Bredesen's clinical trial is published in JAD
As a fellow 4/4, I wish all trials used an exclusively 4/4 dataset but that certainly isn't representative of the general population. In this trial, 16% of the dataset was homozygous, that's actually considerably higher than we're represented in the general population, around 2-3%. I know other work, like the FINGER study, that used a multifactorial approach found that E4s actually responded BETTER than non-E4s. That's very encouraging for our population as it puts control of our fate back into our hands. Yes, a pill would be easier, but until then....
-
- Contributor
- Posts: 9
- Joined: Mon Jun 06, 2022 9:59 pm
Re: Dr. Bredesen's clinical trial is published in JAD
非常感谢,我正在用翻译软件看
The following is the English translation of the software, which may not be accurate. Please forgive me
Thank you very much. I'm reading it with translation software
The following is the English translation of the software, which may not be accurate. Please forgive me
Thank you very much. I'm reading it with translation software
Re: Dr. Bredesen's clinical trial is published in JAD
This is a great update. Thanks for sharing!
"If you are kind only to your friends, how are you different from anyone else?" (Matthew 5:47)
Re: Dr. Bredesen's clinical trial is published in JAD
Your translation is perfect! Thank you for translating the article.Smart Tian wrote: ↑Sat Jul 09, 2022 11:18 pm 非常感谢,我正在用翻译软件看
The following is the English translation of the software, which may not be accurate. Please forgive me
Thank you very much. I'm reading it with translation software
4/4 and still an optimist!