Acetazolamide & Methazolamide Update

[Raziel]

Any thoughts on this? Looks promising:

"Both acetazolamide and methazolamide were highly effective in reducing amyloid deposition and in improving cerebrovascular function," Dr. Fossati said.

"Our behavioral studies showed that, as Alzheimer's pathology decreased, CAI-treated mice experienced noticeable gains in cognitive function."

Both are already FDA-approved for high-altitude sickness and glaucoma.

https://medicalxpress.com/news/2023-04- ... rment.html

[floramaria]

Interesting research and approach. I hadn’t heard of this before. But mice that are engineered to have Alzheimer’s-like pathology are different from humans.

[Raziel]

Humans would be the best solution, but of course mice have the least ethical issues attached to them. Look for wins where we can.