ApoE4 and amino acid metabolism dysfunction

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TheresaB
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ApoE4 and amino acid metabolism dysfunction

Post by TheresaB »

I just came across this paper, Metabolomic and Proteomic Analysis of ApoE4-Carrying H4 Neuroglioma Cells in Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS published by the American Chemical Society on 11 July 2024.

It talks about ApoE4s having lipid disruption (nothing new there) and disruption in amino acid metabolism. To my knowledge, I’d not heard of amino acid dysfunction in us before. Anyone have any insights into this or know of other papers that also address this?
-Theresa
ApoE 4/4
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